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Chronic kidney disease. Chronic kidney disease ( CKD) is a type of long-term kidney disease, in which either there is a gradual loss of kidney function occurs over a period of months to years, or abnormal kidney structure (with normal function). [ 2][ 5] Initially generally no symptoms are seen, but later symptoms may include leg swelling ...
The severity of chronic kidney disease (CKD) is described by six stages; the most severe three are defined by the MDRD-eGFR value, and first three also depend on whether there is other evidence of kidney disease (e.g., proteinuria): 0) Normal kidney function – GFR above 90 (mL/min)/(1.73 m 2) and no proteinuria
Kidney ischemia [ 1] is a disease with a high morbidity and mortality rate. [ 2] Blood vessels shrink and undergo apoptosis which results in poor blood flow in the kidneys. More complications happen when failure of the kidney functions result in toxicity in various parts of the body which may cause septic shock, hypovolemia, and a need for ...
A major measure of kidney function is the glomerular filtration rate ( GFR ). The glomerular filtration rate is the flow rate of filtered fluid through the kidney. The creatinine clearance rate ( CCr or CrCl) is the volume of blood plasma that is cleared of creatinine per unit time and is a useful measure for approximating the GFR.
Medical genetics. Cystic kidney disease refers to a wide range of hereditary, developmental, and acquired conditions [ 1] and with the inclusion of neoplasms with cystic changes, over 40 classifications and subtypes have been identified. Depending on the disease classification, the presentation may be at birth, or much later into adult life.
Kidney cancer, also known as renal cancer, is a group of cancers that starts in the kidney. [ 4] Symptoms may include blood in the urine, a lump in the abdomen, or back pain. [ 1][ 2][ 3] Fever, weight loss, and tiredness may also occur. [ 1][ 2][ 3] Complications can include spread to the lungs or brain. [ 6]
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