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2.5–15% (US) [ 4] Restless legs syndrome, also known as restless leg syndrome ( RLS ), also known as Willis–Ekbom disease ( WED ), is a neurological disorder, usually chronic, that causes an overwhelming urge to move one's legs. [ 2][ 10] There is often an unpleasant feeling in the legs that improves temporarily by moving them. [ 2]
Plummer–Vinson syndrome (also known as Paterson–Kelly syndrome [1] or Paterson–Brown-Kelly syndrome in the UK [2]) is a rare disease characterized by dysphagia (difficulty swallowing), iron-deficiency anemia, glossitis (inflammation of the tongue), cheilosis (cracking at the corners of the mouth), and esophageal webs (thin membranes in the esophagus that can cause obstruction). [1]
Akathisia (IPA: /æ.kə.ˈθɪ.si.ə/) is a movement disorder [ 5] characterized by a subjective feeling of inner restlessness accompanied by mental distress and/or an inability to sit still. [ 6][ 4] Usually, the legs are most prominently affected. [ 2] Those affected may fidget, rock back and forth, or pace, [ 7] while some may just have an ...
54,200 (2015) [ 7] Iron-deficiency anemia is anemia caused by a lack of iron. [ 3] Anemia is defined as a decrease in the number of red blood cells or the amount of hemoglobin in the blood. [ 3] When onset is slow, symptoms are often vague such as feeling tired, weak, short of breath, or having decreased ability to exercise. [ 1]
[medical citation needed] Other symptoms associated with iron deficiency may include brittle nails, cracking at the corner of the mouth, and restless legs syndrome. [14] Severe cases of iron deficiency can also cause the body to make up for decreased oxygen-carrying capacity of the blood by increasing cardiac output .
Iron deficiency, or sideropenia, is the state in which a body lacks enough iron to supply its needs. Iron is present in all cells in the human body and has several vital functions, such as carrying oxygen to the tissues from the lungs as a key component of the hemoglobin protein, acting as a transport medium for electrons within the cells in the form of cytochromes, and facilitating oxygen ...
29.16% (from 48 to 62 per 100,000) and 22.7% (from 3.7 to 4.54 per 100,000) from 2007 to 2014. Heyde's syndrome is a syndrome of gastrointestinal bleeding from angiodysplasia in the presence of aortic stenosis. [ 1][ 2] It is named after Edward C. Heyde, MD, who first noted the association in 1958. [ 3]
Iron metabolism disorders may involve a number of genes including HFE and TFR2. [ 1] Hepcidin is the master regulator of iron metabolism and, therefore, most genetic forms of iron overload can be thought of as relative hepcidin deficiency in one way or another [1]. For instance, a severe form of iron overload, juvenile hemochromatosis, is a ...