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Low-T3 syndrome and high-T3 syndrome: Consequences of step-up hypodeiodination, e.g. in critical illness as an example for type 1 allostasis, or hyperdeiodination, as in type 2 allostasis, including posttraumatic stress disorder. Resistance to thyroid hormone: Feedback loop interrupted on the level of pituitary thyroid hormone receptors.
Neuroendocrinology is also used as an integral part of understanding and treating neurobiological brain disorders. One example is the augmentation of the treatment of mood symptoms with thyroid hormone. Another is the finding of a transthyretin (thyroxine transport) problem in the cerebrospinal fluid of some patients diagnosed with schizophrenia.
Some studies contradict the psychological findings. For example, a large 2002 study found "no statistical association between thyroid dysfunction, and the presence of depression or anxiety disorder." In one study on hospitalised elderly patients, over half had cognitive impairment with either dementia or confusion.
To distinguish his alternative concept from conventional, evidence-based hypothyroidism, he named his concept Wilson's (temperature) syndrome. The main diagnostic sign is an oral body temperature that averages well below 37.0 °C (98.6 °F). This overlaps with normal body temperature, which is usually within the range of 36.5–37.5 °C (97.7 ...
Both excess and deficiency of thyroxine can cause disorders. Hyperthyroidism (an example is Graves' disease) is the clinical syndrome caused by an excess of circulating free thyroxine, free triiodothyronine, or both. It is a common disorder that affects approximately 2% of women and 0.2% of men.
Dissociative identity disorder is characterized by the presence of at least two distinct and relatively enduring personality states. [3] [24] (p331) The disorder is accompanied by memory gaps more severe than could be explained by ordinary forgetfulness. [3] [24] (p331) [25] The personality states alternately show in a person's behavior; [3 ...
Hypothalamic disease is a disorder presenting primarily in the hypothalamus, which may be caused by damage resulting from malnutrition, including anorexia and bulimia eating disorders, [1] [2] genetic disorders, radiation, surgery, head trauma, [3] lesion, [1] tumour or other physical injury to the hypothalamus.
Physiological psychology is a subdivision of behavioral neuroscience (biological psychology) that studies the neural mechanisms of perception and behavior through direct manipulation of the brains of nonhuman animal subjects in controlled experiments. [1] [page needed] This field of psychology takes an empirical and practical approach when ...