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The Pfizer–BioNTech COVID-19 vaccine, sold under the brand name Comirnaty, [2] [32] is an mRNA-based COVID-19 vaccine developed by the German biotechnology company BioNTech. For its development, BioNTech collaborated with the American company Pfizer to carry out clinical trials, logistics, and manufacturing. [44] [45] It is authorized for use ...
More serious side effects are very rare. Before COVID-19 vaccines such as Moderna and Pfizer/BioNTech were authorized for use in the general population, they had to pass phase III studies involving tens of thousands of people. Any serious side effects that did not appear during that testing are likely to occur less often than ~1 in 10,000 cases.
A dynamic, systematic review was established in April 2020 to track the progress of registered clinical trials for COVID-19 vaccine and therapeutic drug candidates. Drug development is a multistep process, typically requiring more than five years to assure safety and efficacy of the new compound.
In a clinical trial involving about 300 people, the most common side effects after the Pfizer booster dose included: Pain, redness and swelling at the injection site. Fatigue. Headache. Muscle and ...
One dose of the updated Pfizer or Moderna mRNA COVID-19 vaccine is recommended for individuals 5 years and older, while two doses of the newly approved Novavax protein-based vaccine are authorized ...
"The benefit-risk profile indicates that serious side effects that have the potential to cause long-term health issues are very rare following the COVID vaccine as opposed to the reported damaging ...
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