Search results
Results From The WOW.Com Content Network
Causes. Having a single palmar crease is often normal. However, it may also be associated with various conditions that affect a person's mental and physical growth, including: Down syndrome. Aarskog syndrome. Cohen syndrome. Fetal alcohol syndrome. Trisomy 13. Rubella syndrome. Turner syndrome. Klinefelter syndrome. Pseudohypoparathyroidism.
An STPC used to be called a “simian crease,” but that term is no longer considered appropriate. STPC can be useful in detecting disorders such as Down syndrome or other developmental problems.
In humans, a single transverse palmar crease is a single crease that extends across the palm of the hand, formed by the fusion of the two palmar creases. Although it is found more frequently in persons with several abnormal medical conditions, it is not predictive of any of these conditions since it is also found in persons with no abnormal ...
32 Hand signs in Down syndrome (trisomy 21) - Phantom picture: simian line (simian crease), Sydney line, atd angle, hand diagnostics, Down's syndrome, fingerprints, fingers, thumb, pinky finger.
What might cause single transverse palmar crease? STPC occurs in about 1 out of every 30 people. In most cases, it is completely normal and is not related to a medical condition. However, it is more likely to be present in people with certain medical conditions, such as: Down syndrome; Fetal alcohol syndrome; Aarskog syndrome
Although simian crease is commonly sought when considering the Down syndrome, these features are not only nonspecific but also occur usually in 50% of cases and, in this study, it is present only in 38.57% of cases of Down syndrome.
The simian crease, aptly named for its resemblance to the palmar creases of nonhuman simian primates, has received recognition clinically and anthropologically owing to its abnormal appearance and confounding cytogenetic etiology.
The single transverse palmar crease, also known as simian crease, is a minor variation associated with Down syndrome (trisomy 21), but also found in 1.5% of the general population [31].
Down syndrome is a genetic disorder caused when abnormal cell division results in an extra full or partial copy of chromosome 21. This extra genetic material causes the developmental changes and physical features of Down syndrome. Down syndrome varies in severity among individuals, causing lifelong intellectual disability and developmental delays.
Practice Essentials. Down syndrome is by far the most common and best known chromosomal disorder in humans and the most common cause of intellectual disability. It is primarily caused by...