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  2. Organic base - Wikipedia

    en.wikipedia.org/wiki/Organic_base

    An organic base is an organic compound which acts as a base. Organic bases are usually, but not always, proton acceptors. They usually contain nitrogen atoms, which can easily be protonated. For example, amines or nitrogen-containing heterocyclic compounds have a lone pair of electrons on the nitrogen atom and can thus act as proton acceptors. [ 1]

  3. Lithium diisopropylamide - Wikipedia

    en.wikipedia.org/wiki/Lithium_diisopropylamide

    Lithium diisopropylamide (commonly abbreviated LDA) is a chemical compound with the molecular formula LiN (CH (CH3)2)2. It is used as a strong base and has been widely utilized due to its good solubility in non-polar organic solvents and non-nucleophilic nature.

  4. Superbase - Wikipedia

    en.wikipedia.org/wiki/Superbase

    Generically IUPAC defines a superbase as a "compound having a very high basicity, such as lithium diisopropylamide ." [ 5] Superbases are often defined in two broad categories, organic and organometallic . Organic superbases are charge-neutral compounds with basicities greater than that of proton sponge (pK BH+ = 18.6 in MeCN)." [ 1]

  5. Base (chemistry) - Wikipedia

    en.wikipedia.org/wiki/Base_(chemistry)

    Base (chemistry) Soaps are weak bases formed by the reaction of fatty acids with sodium hydroxide or potassium hydroxide. In chemistry, there are three definitions in common use of the word " base ": Arrhenius bases, Brønsted bases, and Lewis bases. All definitions agree that bases are substances that react with acids, as originally proposed ...

  6. Organolithium reagent - Wikipedia

    en.wikipedia.org/wiki/Organolithium_reagent

    Organolithium reagent. In organometallic chemistry, organolithium reagents are chemical compounds that contain carbon – lithium (C–Li) bonds. These reagents are important in organic synthesis, and are frequently used to transfer the organic group or the lithium atom to the substrates in synthetic steps, through nucleophilic addition or ...

  7. Non-nucleophilic base - Wikipedia

    en.wikipedia.org/wiki/Non-nucleophilic_base

    Weak. v. t. e. As the name suggests, a non-nucleophilic base is a sterically hindered organic base that is a poor nucleophile. Normal bases are also nucleophiles, but often chemists seek the proton-removing ability of a base without any other functions. Typical non-nucleophilic bases are bulky, such that protons can attach to the basic center ...

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