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DTXSID80166052. Losartan/hydrochlorothiazide, sold under the brand name Hyzaar among others, is a fixed-dose combination medication used to treat high blood pressure when losartan is not sufficient. [ 1][ 2] It consists of losartan (an angiotensin II receptor blocker) and hydrochlorothiazide (a thiazide diuretic ). [ 1][ 2] It is taken by mouth ...
Losartan, sold under the brand name Cozaar among others, is a medication used to treat high blood pressure (hypertension). [4] It is in the angiotensin receptor blocker (ARB) family of medication, and is considered protective of the kidneys.
Hydrochlorothiazide is a thiazide medication which inhibits reabsorption of sodium and chloride ions from the distal convoluted tubules of the kidneys, causing a natriuresis. [ 4][ 5] This initially increases urine volume and lowers blood volume. [ 6] It is believed to reduce peripheral vascular resistance. [ 6]
Hydrochlorothiazide. Chlorthalidone. High blood pressure. 25 mg daily, but may be increased to 50 mg daily. 25 mg daily, but may be increased up to 50–100 mg daily
Antihypertensives are a class of drugs that are used to treat hypertension (high blood pressure). [1] Antihypertensive therapy seeks to prevent the complications of high blood pressure, such as stroke, heart failure, kidney failure and myocardial infarction.
The angiotensin II receptor blockers have differing potencies in relation to blood pressure control, with statistically differing effects at the maximal doses. [11] When used in clinical practice, the particular agent used may vary based on the degree of response required. Some of these drugs have a uricosuric effect. [12] [13]
Legal status. In Wikidata. Renin inhibitors are pharmaceutical drugs inhibiting the activity of renin that is responsible for hydrolyzing angiotensinogen to angiotensin I, [ 2][ 3][ 4] which in turn reduces the formation of angiotensin II that facilitates blood pressure. [ 5][ 6] Renin inhibitor is often preceded by direct, called direct renin ...
Lisinopril is a medication belonging to the drug class of angiotensin-converting enzyme (ACE) inhibitors and is used to treat hypertension (high blood pressure), heart failure, and heart attacks. [7] For high blood pressure it is usually a first-line treatment. It is also used to prevent kidney problems in people with diabetes mellitus. [7]