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Optimer structure with non target binding groups removed for improved Optimer performance and manufacturability. Optimer ligands are short synthetic oligonucleotide molecules composed of DNA or RNA that bind to a specific target molecule. They are engineered to bind their target molecules with affinity typically in the low nanomolar range. [1]
Optimer Pharmaceuticals, Inc. was founded in 1998 and registered in the state of Delaware. Corporate and R&D headquarters were located in San Diego, California until 2011. CEO Michael Nientse Chang founded, funded and built the company with his wife, Tessie Mary Che, who was COO from 1998 to 2011. From 2007 to 2013, Optimer Pharmaceuticals was ...
Until August 3, 2019, telephone numbers in Mexico consisted of ten digits with either two-digit area codes (for Mexico City, Monterrey, and Guadalajara and their respective metropolitan areas) or three-digit area codes for the rest of the country. New area codes were assigned in the overlay format to address number exhaustion: in 2017, Toluca ...
Worldwide distribution of country calling codes. Regions are coloured by first digit. Country calling codes, country dial-in codes, international subscriber dialing (ISD) codes, or most commonly, telephone country codes are telephone number prefixes for reaching telephone subscribers in foreign countries or areas via international telecommunication networks.
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The 600–699 range of area codes in Mexico is reserved for the states of Baja California, Baja California Sur, Chihuahua, Durango, Sinaloa, and Sonora. [ 1] The country code of Mexico is +52. [ 2] For other areas, see Area codes in Mexico by code . City.
Sonora. Tabasco. Tamaulipas. TL. Veracruz. Yucatán. Zacatecas. The states are the first-level administrative divisions of Mexico, which is officially named the United Mexican States. There are 32 federal entities in Mexico (31 states and the capital, Mexico City, as a separate entity that is not formally a state). [ 1][ 2][ 3][ 4]
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