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Melatonin, an indoleamine, is a natural compound produced by various organisms, including bacteria and eukaryotes. [ 1] Its discovery in 1958 by Aaron B. Lerner and colleagues stemmed from the isolation of a substance from the pineal gland of cows that could induce skin lightening in common frogs.
A 2013 review by the National Cancer Institute found insufficient evidence for melatonin having anti-cancer effects. [79] A 2022 review found that melatonin supplementation had a small improvement in survival of people with cancer at one year. [80] [81] One review found that melatonin may alleviate chemotherapy-related side effects. [82]
Diphenhydramine. Diphenhydramine ( DPH) is an antihistamine and sedative mainly used to treat allergies, insomnia, and symptoms of the common cold. It is also less commonly used for tremors in parkinsonism, and nausea. [ 11] It is taken by mouth, injected into a vein, injected into a muscle, or applied to the skin. [ 11]
Research suggests that CBT-I leads to fewer side effects than medication, ... It’s important not to rely on products like ZzzQuil, Benadryl, melatonin gummies, or Advil PM, Wang says. ...
For many, getting a good night’s sleep has not been an easy feat during the pandemic. If you’re looking for an effective sleep, non-habit-forming sleep aid, elevating your nighttime routine ...
Here are her tried-and-true tips after 25 years as a professional traveler: Avoid caffeine: Brown recommends turning down the in-flight coffee service so that the caffeine doesn't keep you up ...
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