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Renal cell carcinoma ( RCC) is a kidney cancer that originates in the lining of the proximal convoluted tubule, a part of the very small tubes in the kidney that transport primary urine. RCC is the most common type of kidney cancer in adults, responsible for approximately 90–95% of cases. [1] It is more common in men (with a male-to-female ...
Generally, the cells have a clear cytoplasm, are surrounded by a distinct cell membrane and contain round and uniform nuclei. [citation needed] Microscopically, CCRCCs are graded by the ISUP/WHO as follows: [1] [2] Grade 1: Inconspicuous and basophilic nucleoli at magnification of 400 times. Grade 2: Clearly visible and eosinophilic nucleoli at ...
Kidney cancer, also known as renal cancer, is a group of cancers that starts in the kidney. [4] Symptoms may include blood in the urine, a lump in the abdomen, or back pain. [1] [2] [3] Fever, weight loss, and tiredness may also occur. [1] [2] [3] Complications can include spread to the lungs or brain. [6]
Signet ring cell carcinoma (SRCC) is a rare form of highly malignant adenocarcinoma [1] that produces mucin. It is an epithelial malignancy characterized by the histologic appearance of signet ring cells . Primary SRCC tumors are most often found in the glandular cells of the stomach (SRCC originates in the stomach in 56 percent of patients ...
Renal medullary carcinoma is a rare type of cancer that affects the kidney.It tends to be aggressive, difficult to treat, and is often metastatic at the time of diagnosis. . Most individuals with this type of cancer have sickle cell trait or rarely sickle cell disease, suggesting that the sickle cell trait may be a risk factor for this type of ca
Papillary renal cell carcinoma (PRCC) is a malignant, heterogeneous tumor originating from renal tubular epithelial cells of the kidney, which comprises approximately 10-15% of all kidney neoplasms. [1] Based on its morphological features, PRCC can be classified into two main subtypes, which are type 1 ( basophilic) and type 2 ( eosinophilic ).
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