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The total dose can be above the threshold for a deterministic effect, but if the dose is spread out over a long period of time, the effect is not observed. Consider the sunburn, a deterministic effect: [ 4 ] when exposed to bright sunlight for only ten minutes [ 5 ] at a high UV Index, that is to say a high average dose rate, [ 6 ] the skin can ...
[20] [74] Oral acetylcysteine is given as a 140 mg/kg loading dose followed by 70 mg/kg every four hours for 17 more doses, and if the patient vomits within 1 hour of dose, the dose must be repeated. [ 75 ] [ 76 ] Oral acetylcysteine may be poorly tolerated due to its unpleasant taste, odor, and its tendency to cause nausea and vomiting. [ 72 ]
Some common causes of nausea are gastroenteritis and other gastrointestinal disorders, food poisoning, motion sickness, dizziness, migraine, fainting, low blood sugar, anxiety, hyperthermia, dehydration and lack of sleep. Nausea is a side effect of many medications including chemotherapy, or morning sickness in early pregnancy.
The ICRP defines two dose quantities for individual committed dose. Committed equivalent dose is the time integral of the equivalent dose rate in a particular tissue or organ that will be received by an individual following intake of radioactive material into the body by a Reference Person, where t is the integration time in years. [3]
Both dose and dose rate contribute to the severity of acute radiation syndrome. The effects of dose fractionation or rest periods before repeated exposure also shift the LD50 dose upwards. Comparison of Radiation Doses – includes the amount detected on the trip from Earth to Mars by the RAD on the MSL (2011–2013).
These dose quantities are weighted averages of absorbed dose designed to be representative of the stochastic health effects of radiation, and use of the sievert implies that appropriate weighting factors have been applied to the absorbed dose measurement or calculation (expressed in grays).
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Pyridoxine, is a form of vitamin B 6 found commonly in food and used as a dietary supplement.As a supplement it is used to treat and prevent pyridoxine deficiency, sideroblastic anaemia, pyridoxine-dependent epilepsy, certain metabolic disorders, side effects or complications of isoniazid use, and certain types of mushroom poisoning. [4]
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