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Melarsoprol. Melarsoprol is an arsenic -containing medication used for the treatment of sleeping sickness (African trypanosomiasis). [ 1] It is specifically used for second-stage disease caused by Trypanosoma brucei rhodesiense when the central nervous system is involved. [ 1] For Trypanosoma brucei gambiense, eflornithine or fexinidazole is ...
Zolpidem, sold under the brand name Ambien among others, is a medication primarily used for the short-term treatment of sleeping problems. [ 10 ] [ 12 ] Guidelines recommend that it be used only after cognitive behavioral therapy for insomnia and after behavioral changes, such as sleep hygiene , have been tried.
3,500 (2015) [ 4] African trypanosomiasis is an insect-borne parasitic infection of humans and other animals. [ 3] Human African trypanosomiasis (HAT), also known as African sleeping sickness or simply sleeping sickness, is caused by the species Trypanosoma brucei. [ 3] Humans are infected by two types, Trypanosoma brucei gambiense (TbG) and ...
The positive opinion is for the treatment of adults and children 6 and older who weigh at least 20 kg (44 lbs), in both the first and second stages of the sickness.
Encephalitis lethargica is an atypical form of encephalitis. Also known as " sleeping sickness " or " sleepy sickness " (distinct from tsetse fly –transmitted sleeping sickness ), it was first described in 1917 by neurologist Constantin von Economo [ 2][ 3] and pathologist Jean-René Cruchet. [ 4] The disease attacks the brain, leaving some ...
Suramin is a medication used to treat African sleeping sickness and river blindness. [ 1][ 2] It is the treatment of choice for sleeping sickness without central nervous system involvement. [ 3] It is given by injection into a vein. [ 4] Suramin causes a fair number of side effects. [ 4] Common side effects include nausea, vomiting, diarrhea ...
As an antihistamine, doxylamine is an inverse agonist of the histamine H 1 receptor. As a first-generation antihistamine, it typically crosses the blood–brain barrier into the brain, thereby producing a suite of sedative and hypnotic effects that are mediated by the central nervous system. (N.b.:
Nifurtimox, sold under the brand name Lampit, is a medication used to treat Chagas disease and sleeping sickness. [ 2][ 4] For sleeping sickness it is used together with eflornithine in nifurtimox-eflornithine combination treatment. [ 4] In Chagas disease it is a second-line option to benznidazole. [ 5] It is given by mouth.
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