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Cryopyrin-associated periodic syndrome ( CAPS) is a group of rare, heterogeneous autoinflammatory disease characterized by interleukin 1β -mediated systemic inflammation and clinical symptoms involving skin, joints, central nervous system, and eyes. It encompasses a spectrum of three clinically overlapping autoinflammatory syndromes including ...
Neonatal-onset multisystem inflammatory disease is a rare genetic periodic fever syndrome which causes uncontrolled inflammation in multiple parts of the body starting in the newborn period. Symptoms include skin rashes, severe arthritis, and chronic meningitis leading to neurologic damage. It is one of the cryopyrin-associated periodic syndromes .
A warning sign is unexplained persistent fever with severe symptoms following exposure to COVID-19. Prompt referral to paediatric specialists is essential, and families need to seek urgent medical assistance. Most affected children will need intensive care. All affected children have persistent fever. Other clinical features vary.
Febrile seizure. A febrile seizure, also known as a fever fit or febrile convulsion, is a seizure associated with a high body temperature but without any serious underlying health issue. [1] They most commonly occur in children between the ages of 6 months and 5 years. [1] [3] Most seizures are less than five minutes in duration, and the child ...
Children continue to have seizures throughout their lives. The term was previously used only for cases that occur in children but was redefined to include all ages. Cause. The cause is not known. There are some common symptoms, such as onset after a nonspecific febrile illness, gastrointestinal illness, or upper respiratory infection.
Periodic fever syndromes are a set of disorders characterized by recurrent episodes of systemic and organ-specific inflammation.Unlike autoimmune disorders such as systemic lupus erythematosus, in which the disease is caused by abnormalities of the adaptive immune system, people with autoinflammatory diseases do not produce autoantibodies or antigen-specific T or B cells.
Acute kidney injury, shock, septic shock, sepsis, multiple organ failure. In immunology, systemic inflammatory response syndrome ( SIRS) is an inflammatory state affecting the whole body. [1] It is the body's response to an infectious or noninfectious insult. Although the definition of SIRS refers to it as an "inflammatory" response, it ...
Influenza-like illness ( ILI ), also known as flu-like syndrome or flu-like symptoms, is a medical diagnosis of possible influenza or other illness causing a set of common symptoms. These include fever, shivering, chills, malaise, dry cough, loss of appetite, body aches, nausea, and sneezing typically in connection with a sudden onset of ...