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Euthyroid sick syndrome. Euthyroid sick syndrome ( ESS) is a state of adaptation or dysregulation of thyrotropic feedback control [1] wherein the levels of T3 and/or T4 are abnormal, but the thyroid gland does not appear to be dysfunctional. This condition may result from allostatic responses of hypothalamus-pituitary-thyroid feedback control ...
Triiodothyronine, also known as T3, is a thyroid hormone. It affects almost every physiological process in the body, including growth and development, metabolism, body temperature, and heart rate. [1]
The main diagnostic sign is an oral body temperature that averages well below 37.0 °C (98.6 °F). This overlaps with normal body temperature, which is usually within the range of 36.5–37.5 °C (97.7–99.5 °F). Wilson says that his diagnosis is confirmed if the patient responds to treatment with slow-release T3 (SR-T3).
The major form of thyroid hormone in the blood is thyroxine (T 4), whose half-life of around one week is longer than that of T 3. In humans, the ratio of T 4 to T 3 released into the blood is approximately 14:1. T 4 is converted to the active T 3 (three to four times more potent than T 4) within cells by deiodinases (5′-deiodinase).
Hyperthyroidism is the condition that occurs due to excessive production of thyroid hormones by the thyroid gland. [3] Thyrotoxicosis is the condition that occurs due to excessive thyroid hormone of any cause and therefore includes hyperthyroidism. [3] Some, however, use the terms interchangeably. [5]
The basal body temperature ranges between 36.7–37.3 °C (98.1–99.1 °F) throughout the luteal phase, and drops down to pre-ovulatory levels within a few days of menstruation. Women can chart this phenomenon to determine whether and when they are ovulating, so as to aid conception or contraception. [citation needed]
If left untreated, the condition can lead to cataracts, increasing weakness in the legs (neuropathy), malnutrition, ketoacidosis, dehydration, and death. [2] Diabetes mainly affects middle-aged and older dogs, but there are juvenile cases. [3] [4] [5] The typical canine diabetes patient is middle-aged, female, and overweight at diagnosis.
In dogs, the thermoneutral zone ranges from 20–30 °C (68–86 °F). In horses, the lower critical temperature is 5 °C while the upper critical temperature depends on the definition used. Their thermoneutral zone is roughly 5–30 °C (41–86 °F).