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Antiretroviral drugs for HIV. Antiviral drugs are a class of medication used for treating viral infections. [1] Most antivirals target specific viruses, while a broad-spectrum antiviral is effective against a wide range of viruses. [2] Antiviral drugs are a class of antimicrobials, a larger group which also includes antibiotic (also termed ...
[8] [11] [10] [17] It contains the antiviral medications nirmatrelvir and ritonavir and was developed by Pfizer. [ 8 ] [ 10 ] Nirmatrelvir inhibits SARS-CoV-2 main protease , while ritonavir is a strong CYP3A inhibitor , slowing down nirmatrelvir metabolism and therefore boosting its effect.
COVID-19. Pfizer. 3C-like protease inhibitor (Nirmatrelvir) / inhibition of metabolism of nirmatrelvir (ritonavir) Nevirapine. HIV. non- nucleoside reverse transcriptase inhibitor. Nitazoxanide. Broad-spectrum antiviral.
Nirmatrelvir. X-ray crystal structure ( PDB:7SI9 and 7VH8) of the SARS-CoV-2 protease inhibitor nirmatrelvir bound to the viral 3CLpro protease enzyme. Ribbon diagram of the protein with the drug shown as sticks. The catalytic residues (His41, Cys145) are shown as yellow sticks. Nirmatrelvir is an antiviral medication developed by Pfizer which ...
Aciclovir, also known as acyclovir, [ 4] is an antiviral medication. [ 5] It is primarily used for the treatment of herpes simplex virus infections, chickenpox, and shingles. [ 6] Other uses include prevention of cytomegalovirus infections following transplant and severe complications of Epstein–Barr virus infection. [ 6][ 7] It can be taken ...
An in vitro study of remdesivir assessing antiviral activity against SARS-CoV-2 was performed. [44] Cells were pre-treated with the different doses of remdesivir for 1 hour, and the virus (MOI of 0.05) was subsequently added to allow infection for 2 hours. [44] The results found that remdesivir functioned well as an inhibitor of the infection. [44]
Antiviral is a 2012 science fiction horror film written and directed by Brandon Cronenberg. The film competed in the Un Certain Regard section at the 2012 Cannes Film Festival . [ 4 ] [ 5 ] Cronenberg re-edited the film after the festival to make it tighter, trimming nearly six minutes out of the film.
Valaciclovir. Valaciclovir, also spelled valacyclovir, is an antiviral medication used to treat outbreaks of herpes simplex or herpes zoster (shingles). [ 2] It is also used to prevent cytomegalovirus following a kidney transplant in high risk cases. [ 2] It is taken by mouth.