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Antiviral is a 2012 science fiction horror film written and directed by Brandon Cronenberg. The film competed in the Un Certain Regard section at the 2012 Cannes Film Festival. [4] [5] Cronenberg re-edited the film after the festival to make it tighter, trimming nearly six minutes out of the film. The revised film was first shown at the 2012 ...
The first successful antiviral, aciclovir, is a nucleoside analogue, and is effective against herpesvirus infections. The first antiviral drug to be approved for treating HIV, zidovudine (AZT), is also a nucleoside analogue. An improved knowledge of the action of reverse transcriptase has led to better nucleoside analogues to treat HIV infections.
List of Antiviral Drugs Antiviral Use Manufacturer Component Type Year approved Abacavir: HIV: ViiV Healthcare: Nucleoside analogue reverse transcriptase inhibitor (NRTI) 1998 Acyclovir (Aciclovir) Herpes Simplex, chickenpox, [2] varicella zoster virus: guanosine analogue RTI 1981 Adefovir: Hepatitis B [3] Gilead Sciences RTI 2002 , 2003 Amantadine
[8] [11] [10] [17] It contains the antiviral medications nirmatrelvir and ritonavir and was developed by Pfizer. [8] [10] Nirmatrelvir inhibits SARS-CoV-2 main protease, while ritonavir is a strong CYP3A inhibitor, slowing down nirmatrelvir metabolism and therefore boosting its effect. [10] [18] It is taken by mouth. [10]
Nirmatrelvir. X-ray crystal structure ( PDB:7SI9 and 7VH8) of the SARS-CoV-2 protease inhibitor nirmatrelvir bound to the viral 3CLpro protease enzyme. Ribbon diagram of the protein with the drug shown as sticks. The catalytic residues (His41, Cys145) are shown as yellow sticks. Nirmatrelvir is an antiviral medication developed by Pfizer which ...
The treatment and management of COVID-19 combines both supportive care, which includes treatment to relieve symptoms, fluid therapy, oxygen support as needed, [1] [2] [3] and a growing list of approved medications. Highly effective vaccines have reduced mortality related to SARS-CoV-2; however, for those awaiting vaccination, as well as for the ...
Aciclovir, also known as acyclovir, [ 4] is an antiviral medication. [ 5] It is primarily used for the treatment of herpes simplex virus infections, chickenpox, and shingles. [ 6] Other uses include prevention of cytomegalovirus infections following transplant and severe complications of Epstein–Barr virus infection. [ 6][ 7] It can be taken ...
Azvudine is an antiviral drug which acts as a reverse transcriptase inhibitor. [3] It was discovered for the treatment of hepatitis C [4] and has since been investigated for use against other viral diseases such as AIDS and COVID-19, [2] [5] for which it was granted conditional approval in China. [6] [7] Azvudine was first discovered in 2007. [8]