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163 million (2017) [ 8] Major depressive disorder ( MDD ), also known as clinical depression, is a mental disorder [ 9] characterized by at least two weeks of pervasive low mood, low self-esteem, and loss of interest or pleasure in normally enjoyable activities. Introduced by a group of US clinicians in the mid-1970s, [ 10] the term was adopted ...
A major depressive episode ( MDE) is a period characterized by symptoms of major depressive disorder. Those affected primarily exhibit a depressive mood for at least two weeks or more, and a loss of interest or pleasure in everyday activities. Other symptoms can include feelings of emptiness, hopelessness, anxiety, worthlessness, guilt ...
Psychotic major depression (PMD), or simply psychotic depression, is the term for a major depressive episode, in particular of melancholic nature, wherein the patient experiences psychotic symptoms such as delusions or, less commonly, hallucinations. These are most commonly mood-congruent (content coincident with depressive themes).
Duloxetine is one of the most commonly used prescription medications in the U.S. Patients with depression are usually prescribed 40 to 60 milligrams per day, with a potential increase of up to 120 ...
Depression is a mental state of low mood and aversion to activity. [ 3] It affects more than 280 million people of all ages (about 3.5% of the global population). [ 4] Depression affects a person's thoughts, behavior, feelings, and sense of well-being. [ 5] Depressed people often experience loss of motivation or interest in, or reduced pleasure ...
For most, the feelings of sadness and emptiness pass with time. However, for some people, it can linger, intensify and even dominate their lives, crippling their ability to go through life.
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