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Wolfram syndrome, also called DIDMOAD ( d iabetes i nsipidus, d iabetes m ellitus, o ptic a trophy, and d eafness), is a rare autosomal-recessive genetic disorder that causes childhood-onset diabetes mellitus, optic atrophy, and deafness as well as various other possible disorders including neurodegeneration.
Diabetes insipidus. Diabetes insipidus ( DI) (arginine vasopressin disorder), alternately called arginine vasopressin deficiency (AVP-D) or arginine vasopressin resistance (AVP-R), [ 5] is a condition characterized by large amounts of dilute urine and increased thirst. [ 1] The amount of urine produced can be nearly 20 liters per day. [ 1]
Primary polydipsia and psychogenic polydipsia are forms of polydipsia [ 1] characterised by excessive fluid intake in the absence of physiological stimuli to drink. [ 2] Psychogenic polydipsia caused by psychiatric disorders—oftentimes schizophrenia —is frequently accompanied by the sensation of dry mouth. Some conditions with polydipsia as ...
Nephrogenic diabetes insipidus, recently renamed arginine vasopressin resistance (AVP-R) and previously known as renal diabetes insipidus, is a form of diabetes insipidus primarily due to pathology of the kidney. This is in contrast to central or neurogenic diabetes insipidus, which is caused by insufficient levels of vasopressin (also called ...
Central diabetes insipidus, recently renamed arginine vasopressin deficiency (AVP-D), [ 1] is a form of diabetes insipidus that is due to a lack of vasopressin (ADH) production in the brain. Vasopressin acts to increase the volume of blood (intravascularly), and decrease the volume of urine produced. Therefore, a lack of it causes increased ...
Polydipsia is excessive thirst or excess drinking. [ 1] The word derives from Greek πολυδίψιος (poludípsios) 'very thirsty', [ 2] which is derived from Ancient Greek πολύς (polús) 'much, many' and δίψα (dípsa) 'thirst'. Polydipsia is a nonspecific symptom in various medical disorders. It also occurs as an abnormal ...
Desmopressin. Desmopressin, sold under the trade name DDAVP among others, is a medication used to treat diabetes insipidus, bedwetting, hemophilia A, von Willebrand disease, and high blood urea levels. [ 1] In hemophilia A and von Willebrand disease, it should only be used for mild to moderate cases. [ 1]
Slowly evolving immune-mediated diabetes, or latent autoimmune diabetes in adults ( LADA ), is a form of diabetes that exhibits clinical features similar to both type 1 diabetes (T1D) and type 2 diabetes (T2D), [ 3][ 4] and is sometimes referred to as type 1.5 diabetes. [ 5] It is an autoimmune form of diabetes, similar to T1D, but patients ...