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The Thyrotroph Thyroid Hormone Sensitivity Index (abbreviated TTSI, also referred to as Thyrotroph T4 Resistance Index or TT4RI) is a calculated structure parameter of thyroid homeostasis. It was originally developed to deliver a method for fast screening for resistance to thyroid hormone. [1] [2] Today it is also used to get an estimate for ...
Normal human body temperature ( normothermia, euthermia) is the typical temperature range found in humans. The normal human body temperature range is typically stated as 36.5–37.5 °C (97.7–99.5 °F). [8] [9] Human body temperature varies. It depends on sex, age, time of day, exertion level, health status (such as illness and menstruation ...
Euthyroid sick syndrome. Euthyroid sick syndrome ( ESS) is a state of adaptation or dysregulation of thyrotropic feedback control [1] wherein the levels of T3 and/or T4 are abnormal, but the thyroid gland does not appear to be dysfunctional. This condition may result from allostatic responses of hypothalamus-pituitary-thyroid feedback control ...
It is used to calculate free thyroxine index (total T4 x T3 uptake), an estimate of free T4. Free thyroxine index may be calculated with increased diagnostic accuracy using direct TBG measurement when the total hormone concentration is abnormally elevated . Examples. In patients with hyperthyroidism, there will be fewer available binding sites ...
Thyroid hormones are any hormones produced and released by the thyroid gland, namely triiodothyronine ( T3) and thyroxine ( T4 ). They are tyrosine -based hormones that are primarily responsible for regulation of metabolism. T 3 and T 4 are partially composed of iodine, derived from food. [2] A deficiency of iodine leads to decreased production ...
Thermal comfort is the condition of mind that expresses subjective satisfaction with the thermal environment. [1] The human body can be viewed as a heat engine where food is the input energy. The human body will release excess heat into the environment, so the body can continue to operate. The heat transfer is proportional to temperature ...
Triiodothyronine, also known as T 3, is a thyroid hormone. It affects almost every physiological process in the body, including growth and development, metabolism, body temperature, and heart rate. Production of T 3 and its prohormone thyroxine (T 4) is activated by thyroid-stimulating hormone (TSH
In humans, hyperthermia is defined as a temperature greater than 37.5–38.3 °C (99.5–100.9 °F), depending on the reference used, that occurs without a change in the body's temperature set point. [3] [10] The normal human body temperature can be as high as 37.7 °C (99.9 °F) in the late afternoon. [2] Hyperthermia requires an elevation ...