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Invasive carcinoma NST is one of the most common types of all breast cancers, accounting for 55% of breast cancer incidence. [2] Of the invasive breast cancers, invasive carcinoma NST accounts for up to 75% of cases. [3] [4] It is also the most common form of breast cancer occurring in men, accounting for 85% of cases. [5] [6]
Breast cancer classification divides breast cancer into categories according to different schemes criteria and serving a different purpose. The major categories are the histopathological type, the grade of the tumor, the stage of the tumor, and the expression of proteins and genes .
Triple-negative breast cancer comprises 15–20% of all breast cancer cases [3] and affects more young women or women with a mutation in the BRCA1 gene than other breast cancers. [4] Triple-negative breast cancers comprise a very heterogeneous group of cancers. TNBC is the most challenging breast cancer type to treat. [5]
Triple-negative breast cancer (up to 15% of cases) and inflammatory breast cancer (up to 5% of cases) are particularly aggressive and have relatively poor prognoses. [ 82 ] [ 83 ] Those with triple-negative breast cancer have an overall five-year survival rate of 77% – 91% for those whose tumors are confined to the breast; 12% for those with ...
Histopathologic types of breast cancer, with relative incidences and prognoses, with "invasive lobular carcinoma" at top right. Invasive lobular carcinoma (ILC) is breast cancer arising from the lobules of the mammary glands. [ 1] It accounts for 5–10% of invasive breast cancer. [ 2][ 3] Rare cases of this carcinoma have been diagnosed in men ...
BRCA-related breast cancer appears at an earlier age than sporadic breast cancer. [9]: 89–111 It has been asserted that BRCA-related breast cancer is more aggressive than normal breast cancer, however most studies in specific populations suggest little or no difference in survival rates despite seemingly worse prognostic factors. [11] [12] [13]
In response to her diagnosis, her close friends launched the TNBC Foundation to raise awareness and support research for this particular type of breast cancer. [2] Block-Zenna died of the disease in 2007, 2 1 ⁄ 2 years after her diagnosis. [2] At the time, little was known about triple negative breast cancer, and research efforts were minimal.
Metastatic breast cancer. Metastatic breast cancer, also referred to as metastases, advanced breast cancer, secondary tumors, secondaries or stage IV breast cancer, is a stage of breast cancer where the breast cancer cells have spread to distant sites beyond the axillary lymph nodes. There is no cure for metastatic breast cancer; [ 1] there is ...