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He also began the practice of neutralization of certain antibodies in the blood of universal blood donors. In 1957, he co-authored a paper the "Witebsky's postulates" which determined whether a disease entity could be regarded as an autoimmune disease: [4] Direct demonstration of free circulating antibodies active at body temperature.
Griffith's experiment, [ 1] performed by Frederick Griffith and reported in 1928, [ 2] was the first experiment suggesting that bacteria are capable of transferring genetic information through a process known as transformation. [ 3][ 4] Griffith's findings were followed by research in the late 1930s and early 40s that isolated DNA as the ...
The Avery–MacLeod–McCarty experiment was an experimental demonstration by Oswald Avery, Colin MacLeod, and Maclyn McCarty that, in 1944, reported that DNA is the substance that causes bacterial transformation, in an era when it had been widely believed that it was proteins that served the function of carrying genetic information (with the ...
Blood compatibility testing is routinely performed before a blood transfusion. The full compatibility testing process involves ABO and RhD (Rh factor) typing; screening for antibodies against other blood group systems; and crossmatching, which involves testing the recipient's blood plasma against the donor's red blood cells as a final check for ...
Nazi human experimentation was a series of medical experiments on prisoners by Nazi Germany in its concentration camps mainly between 1942 and 1945. There were 15,754 documented victims, of various nationalities and age groups, although the true number is believed to be more extensive. Many survived, with a quarter of documented victims being ...
Unit 731 (Japanese: 731部隊, Hepburn: Nana-san-ichi Butai), [note 1] short for Manchu Detachment 731 and also known as the Kamo Detachment [3]: 198 and the Ishii Unit, [5] was a covert biological and chemical warfare research and development unit of the Imperial Japanese Army that engaged in lethal human experimentation and biological weapons manufacturing during the Second Sino-Japanese War ...
Dunnett's test's calculation is a procedure that is based on calculating confidence statements about the true or the expected values of the differences , thus the differences between treatment groups' mean and control group's mean. This procedure ensures that the probability of all statements being simultaneously correct is equal to a specified ...
The thyroid hormones cross the follicular cell membrane towards the blood vessels by an unknown mechanism. [31] Text books have stated that diffusion is the main means of transport, [ 35 ] but recent studies indicate that monocarboxylate transporter (MCT) 8 and 10 play major roles in the efflux of the thyroid hormones from the thyroid cells.