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As of 2024, Pennsylvania's gross state product (GSP) of $1.0 trillion is the sixth-largest among all U.S. states behind California, Texas, New York, Florida, and Illinois. [ 144 ] If Pennsylvania were an independent country , its economy, as of 2023, would rank as the 20th-largest in the world. [ 145 ]
In 2021, gold extraction generated around 2.3 billion dollars, of which the State received only 25%. [ 38 ] [ 39 ] [ 40 ] By 2023, the economic situation of Venezuela improved, with the economy growing by 15% and extreme poverty rates decreasing, thanks to a liberalized economy and more access to the United States dollar .
The intravenous dose causing 50% of opioid-naive experimental subjects to die (LD 50) is "3 mg/kg in rats, 1 mg/kg in cats, 14 mg/kg in dogs, and 0.03 mg/kg in monkeys." [ 96 ] The LD 50 in mice has been given as 6.9 mg/kg by intravenous administration, 17.5 mg/kg intraperitoneally, 27.8 mg/kg by oral administration. [ 97 ]
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