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Triiodothyronine, also known as T3, is a thyroid hormone. It affects almost every physiological process in the body, including growth and development, metabolism, body temperature, and heart rate.
The major form of thyroid hormone in the blood is thyroxine (T 4 ), whose half-life of around one week [4] is longer than that of T 3. [5] In humans, the ratio of T 4 to T 3 released into the blood is approximately 14:1. [6] T 4 is converted to the active T 3 (three to four times more potent than T 4) within cells by deiodinases (5′-deiodinase). These are further processed by decarboxylation ...
The hypothalamus senses low circulating levels of thyroid hormone ( Triiodothyronine (T3) and Thyroxine (T4)) and responds by releasing thyrotropin-releasing hormone (TRH). The TRH stimulates the anterior pituitary to produce thyroid-stimulating hormone (TSH). The TSH, in turn, stimulates the thyroid to produce thyroid hormone until levels in the blood return to normal. Thyroid hormone exerts ...
Thyroid function tests ( TFTs) is a collective term for blood tests used to check the function of the thyroid. [1] TFTs may be requested if a patient is thought to suffer from hyperthyroidism (overactive thyroid) or hypothyroidism (underactive thyroid), or to monitor the effectiveness of either thyroid-suppression or hormone replacement therapy.
Wilson's ( temperature) syndrome, also called Wilson's thyroid syndrome or WTS, is a term used in alternative medicine to improperly attribute various common and non-specific symptoms to abnormally low body temperature and impaired conversion of thyroxine (T4) to triiodothyronine (T3), despite normal thyroid function tests. [1] E. Denis Wilson, a physician who invented the concept and named it ...
Normal human body temperature ( normothermia, euthermia) is the typical temperature range found in humans. The normal human body temperature range is typically stated as 36.5–37.5 °C (97.7–99.5 °F). [8] [9] Human body temperature varies. It depends on sex, age, time of day, exertion level, health status (such as illness and menstruation ...
Reverse triiodothyronine (3,3′,5′-triiodothyronine, reverse T 3, or rT 3) is an isomer of triiodothyronine (3,5,3′ triiodothyronine, T 3 ). Reverse T 3 is the third-most common iodothyronine the thyroid gland releases into the bloodstream, at 0.9%; tetraiodothyronine (levothyroxine, T 4) constitutes 90% and T 3 is 9%.
Hyperthyroidism is the condition that occurs due to excessive production of thyroid hormones by the thyroid gland. [3] Thyrotoxicosis is the condition that occurs due to excessive thyroid hormone of any cause and therefore includes hyperthyroidism. [3] Some, however, use the terms interchangeably. [5] Signs and symptoms vary between people and may include irritability, muscle weakness ...