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Melatonin is a dietary supplement and medication as well as naturally occurring hormone. [9] [12] As a hormone, melatonin is released by the pineal gland and is involved in sleep–wake cycles. [9] [12] As a supplement, it is often used for the attempted short-term treatment of disrupted sleep patterns, such as from jet lag or shift work, and ...
Postoperative cognitive dysfunction ( POCD) is a decline in cognitive function (especially in memory and executive functions) that may last from 1–12 months after surgery, or longer. [1] In some cases, this disorder may persist for several years after major surgery. [2] POCD is distinct from emergence delirium.
Melatonin, an indoleamine, is a natural compound produced by various organisms, including bacteria and eukaryotes. [1] Its discovery in 1958 by Aaron B. Lerner and colleagues stemmed from the isolation of a substance from the pineal gland of cows that could induce skin lightening in common frogs.
Sleep medicine is a medical specialty or subspecialty devoted to the diagnosis and therapy of sleep disturbances and disorders. [1] From the middle of the 20th century, research has provided increasing knowledge of, and answered many questions about, sleep–wake functioning. [2] The rapidly evolving field [3] has become a recognized medical ...
Zolpidem, sold under the brand name Ambien among others, is a medication primarily used for the short-term treatment of sleeping problems. [10] [12] Guidelines recommend that it be used only after cognitive behavioral therapy for insomnia and after behavioral changes, such as sleep hygiene, have been tried.
Insomnia, also known as sleeplessness, is a sleep disorder where people have trouble sleeping. [1] They may have difficulty falling asleep, or staying asleep for as long as desired. [1] [9] [11] Insomnia is typically followed by daytime sleepiness, low energy, irritability, and a depressed mood. [1] It may result in an increased risk of ...
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