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Among the 284 patients that were studied, 33% of the patients developed irreversible dementia while 53% of the patients no longer met the criteria for dementia during follow-up. [34] Individuals with pseudodementia present considerable cognitive deficits, including disorders in learning, memory and psychomotor performance.
Before dementia develops (during the mild cognitive impairment phase), MRI scans show normal hippocampal volume. After dementia develops, MRI shows more atrophy among individuals with AD, and a slower reduction in volume over time among people with DLB than those with AD. [33]
Dementia with Lewy bodies and Parkinson's disease dementia are similar in many ways, suggesting there may be a common pathophysiological mechanism, with PDD and DLB at opposite ends of a Lewy body disease spectrum, [2] and a shared component of protein deposits in Lewy bodies and Lewy neurites. [16]
Screening for dementia in the English NHS is controversial because it could cause undue anxiety in patients and support services would be stretched. A GP reported "The main issue really seems to be centred around what the consequences of a such a diagnosis is and what is actually available to help patients."
Aktion T4 (German, pronounced [akˈtsi̯oːn teː fiːɐ]) was a campaign of mass murder by involuntary euthanasia in Nazi Germany.The term was first used in post-war trials against doctors who had been involved in the killings. [4]
Dementia in the elderly was once called senile dementia or senility, and viewed as a normal and somewhat inevitable aspect of aging. [283] [284] By 1913–20 the term dementia praecox was introduced to suggest the development of senile-type dementia at a younger age.
However, the MMSE scores may be used to classify the severity of cognitive impairment or to document serial change in dementia patients. The following four cut-off levels should be employed to classify the severity of cognitive impairment: no cognitive impairment 24–30; mild cognitive impairment 19–23; moderate cognitive impairment 10–18 ...
Other studies have tested the MoCA on patients with Alzheimer's disease. [6] [7] [8] People with hearing loss, which commonly occurs alongside dementia, score worse in the MoCA test, which could lead to a false diagnosis of dementia. Researchers have developed an adapted version of the MoCA test, which is accurate and reliable and avoids the ...