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Red blood cell distribution width ( RDW ), as well as various types thereof ( RDW-CV or RCDW and RDW-SD ), is a measure of the range of variation of red blood cell (RBC) volume that is reported as part of a standard complete blood count. [ 1] Red blood cells have an average volume of 80–100 femtoliters, but individual cell volumes vary even ...
A complete blood count ( CBC ), also known as a full blood count ( FBC ), is a set of medical laboratory tests that provide information about the cells in a person's blood. The CBC indicates the counts of white blood cells, red blood cells and platelets, the concentration of hemoglobin, and the hematocrit (the volume percentage of red blood ...
Red blood cell distribution width (RDW or RDW-CV or RCDW and RDW-SD) is a measure of the range of variation of red blood cell (RBC) volume, yielding clues about morphology. [ citation needed ] Erythropoietic precursor indices
Sideroblastic anemia, or sideroachrestic anemia, is a form of anemia in which the bone marrow produces ringed sideroblasts rather than healthy red blood cells (erythrocytes). [ 1] In sideroblastic anemia, the body has iron available but cannot incorporate it into hemoglobin, which red blood cells need in order to transport oxygen efficiently.
Hereditary spherocytosis ( HS) is a congenital hemolytic disorder wherein a genetic mutation coding for a structural membrane protein phenotype causes the red blood cells to be sphere-shaped ( spherocytosis ), rather than the normal biconcave disk shape. This abnormal shape interferes with the cells' ability to flex during blood circulation ...
A low hematocrit level is a sign of a low red blood cell count. One way to increase the ability of oxygen transport in red blood cells is through blood transfusion, which is carried out typically when the red blood cell count is low. Prior to the blood transfusion, hematocrit levels are measured to help ensure the transfusion is necessary and safe.
Microangiopathic hemolytic anemia may be suspected based on routine medical laboratory tests such as a CBC (complete blood cell count). Automated analysers (the machines that perform routine full blood counts in most hospitals) are designed to flag blood specimens that contain abnormal amounts of red blood cell fragments or schistocytes. [2]
An anemia is a red blood cell defect that can lead to an undersupply of oxygen. [ 1] Megaloblastic anemia results from inhibition of DNA synthesis during red blood cell production. [ 2] When DNA synthesis is impaired, the cell cycle cannot progress from the G2 growth stage to the mitosis (M) stage. This leads to continuing cell growth without ...
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