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Red blood cell distribution width ( RDW ), as well as various types thereof ( RDW-CV or RCDW and RDW-SD ), is a measure of the range of variation of red blood cell (RBC) volume that is reported as part of a standard complete blood count. [ 1] Red blood cells have an average volume of 80–100 femtoliters, but individual cell volumes vary even ...
An anemia is a red blood cell defect that can lead to an undersupply of oxygen. [ 1] Megaloblastic anemia results from inhibition of DNA synthesis during red blood cell production. [ 2] When DNA synthesis is impaired, the cell cycle cannot progress from the G2 growth stage to the mitosis (M) stage. This leads to continuing cell growth without ...
Sideroblastic anemia, or sideroachrestic anemia, is a form of anemia in which the bone marrow produces ringed sideroblasts rather than healthy red blood cells (erythrocytes). [ 1] In sideroblastic anemia, the body has iron available but cannot incorporate it into hemoglobin, which red blood cells need in order to transport oxygen efficiently.
54,200 (2015) [ 7] Iron-deficiency anemia is anemia caused by a lack of iron. [ 3] Anemia is defined as a decrease in the number of red blood cells or the amount of hemoglobin in the blood. [ 3] When onset is slow, symptoms are often vague such as feeling tired, weak, short of breath, or having decreased ability to exercise. [ 1]
Hereditary spherocytosis ( HS) is a congenital hemolytic disorder wherein a genetic mutation coding for a structural membrane protein phenotype causes the red blood cells to be sphere-shaped ( spherocytosis ), rather than the normal biconcave disk shape. This abnormal shape interferes with the cells' ability to flex during blood circulation ...
Red blood cell distribution width (RDW or RDW-CV or RCDW and RDW-SD) is a measure of the range of variation of red blood cell (RBC) volume, yielding clues about morphology. [ citation needed ] Erythropoietic precursor indices
1 per 1000 people [ 8] Pernicious anemia is a disease where not enough red blood cells are produced due to a deficiency of vitamin B 12. [ 5] Those affected often have a gradual onset. [ 5] The most common initial symptoms are feeling tired and weak. [ 4]
Human red blood cells from a case of anisocytosis. Anisocytosis is a medical term meaning that a patient's red blood cells are of unequal size. This is commonly found in anemia and other blood conditions. False diagnostic flagging may be triggered on a complete blood count by an elevated WBC count, agglutinated RBCs, RBC fragments, giant ...