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  2. Type 2 diabetes - Wikipedia

    en.wikipedia.org/wiki/Type_2_diabetes

    392 million (2015) [ 11] Type 2 diabetes ( T2D ), formerly known as adult-onset diabetes, is a form of diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin. [ 6] Common symptoms include increased thirst, frequent urination, fatigue and unexplained weight loss. [ 3]

  3. Genetic causes of type 2 diabetes - Wikipedia

    en.wikipedia.org/wiki/Genetic_causes_of_type_2...

    Polygenic. Genetic cause and mechanism of type 2 diabetes is largely unknown. However, single nucleotide polymorphism (SNP) is one of many mechanisms that leads to increased risk for type 2 diabetes. To locate genes and loci that are responsible for the risk of type 2 diabetes, genome wide association studies (GWAS) was utilized to compare the ...

  4. Diabetes - Wikipedia

    en.wikipedia.org/wiki/Diabetes

    4.2 million (2019) [ 9] Diabetes mellitus, often known simply as diabetes, is a group of common endocrine diseases characterized by sustained high blood sugar levels. [ 10][ 11] Diabetes is due to either the pancreas not producing enough insulin, or the cells of the body becoming unresponsive to the hormone's effects. [ 12]

  5. Outline of diabetes - Wikipedia

    en.wikipedia.org/wiki/Outline_of_diabetes

    Lifestyle causes of diabetes mellitus type 2; Related conditions. Impaired glucose tolerance – Preventing diabetes mellitus Preventing diabetes mellitus type 1. Currently, there is no known way to prevent diabetes mellitus type 1. However, onset of diabetes mellitus type 1 may be delayed by about two years by administering Teplizumab ...

  6. Many diagnosed with Type 2 diabetes may actually have a ... - AOL

    www.aol.com/news/many-diagnosed-type-2-diabetes...

    The condition is often called latent autoimmune diabetes of adults, or LADA for short. Patients with it can be misdiagnosed with Type 2 diabetes and spend months or years trying to manage the ...

  7. History of diabetes - Wikipedia

    en.wikipedia.org/wiki/History_of_diabetes

    Philip Hugh-Jones, while working in Jamaica in 1955, clarified Lawrence's classification and coined the terms "type 1" and "type 2" diabetes. He also noted a rarer variety observed in insulin-resistant youth (whose condition could not be placed into the two types). He called this third group "type J", where J stood for Jamaica.

  8. Insulin - Wikipedia

    en.wikipedia.org/wiki/Insulin

    There are two types of the disease. In type 1 diabetes , the beta cells are destroyed by an autoimmune reaction so that insulin can no longer be synthesized or be secreted into the blood. [ 12 ] In type 2 diabetes , the destruction of beta cells is less pronounced than in type 1, and is not due to an autoimmune process.

  9. Epigenetics of diabetes type 2 - Wikipedia

    en.wikipedia.org/wiki/Epigenetics_of_diabetes_Type_2

    The PPARGC1A gene regulates genes involved in energy metabolism. [1] [2] Since type 2 diabetes is characterized by chronic hyperglycaemia as a result of impaired pancreatic beta cell function [3] and insulin resistance in peripheral tissues, [4] it was thought that the gene might be downregulated in type 2 diabetes patients through DNA methylation.

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