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The disorder results from an antibody, called thyroid-stimulating immunoglobulin (TSI), that has a similar effect to thyroid stimulating hormone (TSH). [1] These TSI antibodies cause the thyroid gland to produce excess thyroid hormones. [1] The diagnosis may be suspected based on symptoms and confirmed with blood tests and radioiodine uptake.
Thyroid storm is a severe form of thyrotoxicosis characterized by rapid and often irregular heart beat, high temperature, vomiting, diarrhea, and mental agitation. Symptoms may not be typical in the young, old, or pregnant. [2] It usually occurs due to untreated hyperthyroidism and can be provoked by infections. [2]
Harlequin syndrome. A man exhibiting the asymmetric symptoms of Harlequin syndrome. One half of the forehead is more red than the other. Harlequin syndrome is a condition characterized by asymmetric sweating and flushing on the upper thoracic region of the chest, neck and face. Harlequin syndrome is considered an injury to the autonomic nervous ...
Most frequent are symptoms due to conjunctival or corneal irritation: burning, photophobia, tearing, pain, and a gritty or sandy sensation. [4] Protruding eyeballs (known as proptosis and exophthalmos ). Diplopia (double vision) is common. [4] Limitation of eye movement (due to impairment of eye muscle function).
Heat intolerance is a symptom characterized by feeling overheated in warm environments or when the surrounding environment's temperature rises. [1] Typically, the person feels uncomfortably hot and sweats excessively. Compared to heat illnesses like heatstroke, heat intolerance is usually a symptom of endocrine disorders, drugs, or other ...
Thyroid disease is a medical condition that affects the function of the thyroid gland. The thyroid gland is located at the front of the neck and produces thyroid hormones [ 1] that travel through the blood to help regulate many other organs, meaning that it is an endocrine organ. These hormones normally act in the body to regulate energy use ...
Heat illness is a spectrum of disorders due to increased body temperature. It can be caused by either environmental conditions or by exertion. It includes minor conditions such as heat cramps, heat syncope, and heat exhaustion as well as the more severe condition known as heat stroke. [ 1] It can affect any or all anatomical systems. [ 2]
At the cellular level, T 3 is the body's more active and potent thyroid hormone. [2] T 3 helps deliver oxygen and energy to all of the body's cells, its effects on target tissues being roughly four times more potent than those of T 4. [2] Of the thyroid hormone that is produced, just about 20% is T 3, whereas 80% is produced as T 4.