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Diabetes mellitus, often known simply as diabetes, is a group of common endocrine diseases characterized by sustained high blood sugar levels. [ 10][ 11] Diabetes is due to either the pancreas not producing enough insulin, or the cells of the body becoming unresponsive to the hormone's effects. [ 12] Classic symptoms include thirst, polyuria ...
Polygenic. Genetic cause and mechanism of type 2 diabetes is largely unknown. However, single nucleotide polymorphism (SNP) is one of many mechanisms that leads to increased risk for type 2 diabetes. To locate genes and loci that are responsible for the risk of type 2 diabetes, genome wide association studies (GWAS) was utilized to compare the ...
Type 2 diabetes (T2D), formerly known as adult-onset diabetes, is a form of diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin. [6] Common symptoms include increased thirst , frequent urination , fatigue and unexplained weight loss . [ 3 ]
A blue circle, the symbol for diabetes. High blood sugar levels, autoantibodies targeting insulin-producing cells. Type 1 diabetes ( T1D ), formerly known as juvenile diabetes, is an autoimmune disease that originates when cells that make insulin (beta cells) are destroyed by the immune system. [ 5] Insulin is a hormone required for the cells ...
Type 2 diabetesA little more than 1 in 10 Americans -- or 34.2 million -- have diabetes, according to the American Diabetes Association.
Epidemiology of diabetes. Prevalence (per 1,000 inhabitants) of diabetes worldwide in 2000 - world average was 2.8%. Globally, an estimated 537 million adults are living with diabetes, according to 2019 data from the International Diabetes Federation. [ 1] Diabetes was the 9th-leading cause of mortality globally in 2020, attributing to over 2 ...
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