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Gamma secretase complexes have also been observed localized to the mitochondria, where they may play a role in promoting apoptosis. Function. Gamma secretase is an internal protease that cleaves within the membrane-spanning domain of its substrate proteins, including amyloid precursor protein (APP) and Notch.
The gamma function is an important special function in mathematics. Its particular values can be expressed in closed form for integer and half-integer arguments, but no simple expressions are known for the values at rational points in general. Other fractional arguments can be approximated through efficient infinite products, infinite series ...
Gamma (stylized as gamma. with a full stop) is an American media company founded in 2023 by former Apple executive Larry Jackson and record executive Ike Youssef. Described as a competitor to major labels , the company acts as an alternative distributor for multimedia content by means of a prior acquisition of the technology platform Vydia. [2]
Processing of the amyloid-beta precursor protein. Secretases are enzymes that "snip" pieces off a longer protein that is embedded in the cell membrane . Among other roles in the cell, secretases act on the amyloid-beta precursor protein (APP) to cleave the protein into three fragments. [citation needed] Sequential cleavage by beta-secretase 1 ...
Gamma waves. A gamma wave or gamma rhythm is a pattern of neural oscillation in humans with a frequency between 25 and 140 Hz, the 40 Hz point being of particular interest. [1] Gamma rhythms are correlated with large-scale brain network activity and cognitive phenomena such as working memory, attention, and perceptual grouping, and can be ...
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Alpha secretases are a family of proteolytic enzymes that cleave amyloid precursor protein (APP) in its transmembrane region. Specifically, alpha secretases cleave within the fragment that gives rise to the Alzheimer's disease -associated peptide amyloid beta when APP is instead processed by beta secretase and gamma secretase.
Gamma (/ ˈ ɡ æ m ə /; uppercase Γ, lowercase γ; Greek: γάμμα, romanized: gámma) is the third letter of the Greek alphabet. In the system of Greek numerals it has a value of 3. In Ancient Greek , the letter gamma represented a voiced velar stop IPA: [ɡ] .