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[1] [2] Most of the developed modafinil analogues are selective DRIs with improved potency . [ 3 ] [ 2 ] [ 4 ] They are of interest in the potential treatment of psychostimulant use disorder (PSUD), [ 3 ] [ 2 ] [ 5 ] [ 6 ] as pro-motivational agents to treat motivational disorders , [ 4 ] [ 7 ] and for treatment of certain other conditions ...
Modafinil, sold under the brand name Provigil among others, is a wakefulness-promoting medication used primarily to treat narcolepsy, [3] [10] [15] a sleep disorder characterized by excessive daytime sleepiness and sudden sleep attacks. [16]
Cast Away is a 2000 American survival drama film directed and produced by Robert Zemeckis and starring Tom Hanks, Helen Hunt, and Nick Searcy. Hanks plays a FedEx troubleshooter who is stranded on an uninhabited island after his plane crashes in the South Pacific, and the plot focuses on his desperate attempts to survive and return home. Initial filming took place from January to March 1999 ...
Labor Day is almost here, and the three-day weekend is the perfect time to catch up on online shopping. Amazon is brimming with innumerable deals on all the kitchen essentials you need to live a ...
The intravenous dose causing 50% of opioid-naive experimental subjects to die (LD 50) is "3 mg/kg in rats, 1 mg/kg in cats, 14 mg/kg in dogs, and 0.03 mg/kg in monkeys." [ 96 ] The LD 50 in mice has been given as 6.9 mg/kg by intravenous administration, 17.5 mg/kg intraperitoneally, 27.8 mg/kg by oral administration. [ 97 ]
In the world of economics and finance, a 'bellwether' is a leading indicator of an economic trend. [1] [2]In the stock market, a 'bellwether' is a company or stock taken to be a leading indicator of the direction in a sector, in an industry or in the market as a whole.
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