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In Wikidata. Calcium channel blockers ( CCB ), calcium channel antagonists or calcium antagonists[ 2] are a group of medications that disrupt the movement of calcium ( Ca2+. ) through calcium channels. [ 3] Calcium channel blockers are used as antihypertensive drugs, i.e., as medications to decrease blood pressure in patients with hypertension.
Compared with certain other L-type calcium channel blockers (for example those of the phenylalkylamine class such as verapamil) that have significant action at the heart, the dihydropyridine calcium channel blockers lower blood pressure mainly by relaxing the smooth muscle of the blood vessel walls. [3]
Amlodipine. Amlodipine, sold under the brand name Norvasc among others, is a calcium channel blocker medication used to treat high blood pressure, coronary artery disease (CAD) [ 10] and variant angina (also called Prinzmetal angina or coronary artery vasospasm, among other names). [ 11] It is taken orally (swallowed by mouth).
A calcium channel is an ion channel which shows selective permeability to calcium ions. It is sometimes synonymous with voltage-gated calcium channel, [ 1] which are a type of calcium channel regulated by changes in membrane potential. Some calcium channels are regulated by the binding of a ligand. [ 2][ 3] Other calcium channels can also be ...
An L-type calcium channel with its subunits labeled along with some drugs known to inhibit the channel. The L-type calcium channel (also known as the dihydropyridine channel, or DHP channel) is part of the high-voltage activated family of voltage-dependent calcium channel. [ 2] ". L" stands for long-lasting referring to the length of activation.
Nifedipine. Nifedipine, sold under the brand name Procardia among others, is a calcium channel blocker medication used to manage angina, high blood pressure, Raynaud's phenomenon, and premature labor. [ 2] It is one of the treatments of choice for Prinzmetal angina. [ 2] It may be used to treat severe high blood pressure in pregnancy. [ 2]
N-type calcium channels are categorized as high threshold-activated channels and seen in the Cav2 gene family. The structure of the N-type calcium channel is very similar to other voltage-dependent channels. The most important part of the channel is the actual pore that is formed by the α1B subunit.
Pages in category "Calcium channel blockers" The following 98 pages are in this category, out of 98 total. This list may not reflect recent changes. ...
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