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Alzheimer's disease ( AD) is a neurodegenerative disease that usually starts slowly and progressively worsens, [ 2] and is the cause of 60–70% of cases of dementia. [ 2][ 15] The most common early symptom is difficulty in remembering recent events. [ 1] As the disease advances, symptoms can include problems with language, disorientation ...
Alois Alzheimer. Alois Alzheimer ( / ˈæltshaɪmər / ALTS-hy-mər, US also / ˈɑːlts -, ˈɔːlts -/ AHLTS-, AWLTS-, [1] [2] German: [ˈaːlɔɪs ˈʔaltshaɪmɐ]; 14 June 1864 – 19 December 1915) was a German psychiatrist and neuropathologist and a colleague of Emil Kraepelin. Alzheimer is credited with identifying the first published ...
Dementia is a syndrome associated with many neurodegenerative diseases, characterized by a general decline in cognitive abilities that affects a person's ability to perform everyday activities. This typically involves problems with memory, thinking, behavior, and motor control. [10]
Early-onset Alzheimer's disease ( EOAD ), also called younger-onset Alzheimer's disease ( YOAD ), [1] is Alzheimer's disease diagnosed before the age of 65. [2] It is an uncommon form of Alzheimer's, accounting for only 5–10% of all Alzheimer's cases. About 60% have a positive family history of Alzheimer's and 13% of them are inherited in an ...
The Alzheimer's Disease and Related Disorders Association was incorporated on April 10, 1980. In that year, the National Institutes of Health (NIH) invested $13 million in Alzheimer's disease research. In 1982, President Ronald Reagan designated the first National Alzheimer's Disease Awareness Week. The Association is the world's largest ...
A new study has uncovered unique molecular signatures linked to the disruption of this blood-brain barrier in Alzheimer’s disease. These findings could lead to new ways of using biomarkers in ...
The biochemistry of Alzheimer's disease, the most common cause of dementia, is not yet very well understood. Alzheimer's disease (AD) has been identified as a proteopathy: a protein misfolding disease due to the accumulation of abnormally folded amyloid beta (Aβ) protein in the brain. [1] Amyloid beta is a short peptide that is an abnormal ...
APOE-e4 gene increases ARIA side effect risk. In addition to having an increased risk for Alzheimer’s disease, Sabalza said people with the APOE-e4 allele are also more likely to experience the ...
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