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Cetylpyridinium chloride is known to cause tooth staining in approximately 3 percent of users. [14] The Crest brand has noted that this staining is actually an indication that the product is working as intended, as the stains are a result of bacteria dying on the teeth. [15]
Sulfonylureas — effects enhanced; Phenytoin, half-life of phenytoin is increased; Antifolates like pyrimethamine, proguanil and methotrexate increase the risk of associated side effects like bone marrow toxicity, folic acid supplementation should be considered. A significant risk of megaloblastic anaemia exists with doses of pyrimethamine in ...
The Prohibition era was the period from 1920 to 1933 when the United States prohibited the production, importation, transportation, and sale of alcoholic beverages. [1] The alcohol industry was curtailed by a succession of state legislatures, and Prohibition was formally introduced nationwide under the Eighteenth Amendment to the United States Constitution, ratified on January 16, 1919.
The Food and Drug Administration began to review the safety of triclocarban and triclosan in the 1970s, but due to the difficulties of finding antimicrobial alternatives, no final policy, or "drug monograph," was established. [20] Legal action by the Natural Resources Defense Council in 2010 forced the FDA to review triclocarban and triclosan. [20]
The rock and roll lifestyle was popularly associated with sex and drugs. Many of rock and roll's early stars (as well as their jazz and blues counterparts) were known as hard-drinking, hard-living characters. During the 1960s the lifestyles of many stars became more publicly known, aided by the growth of the underground rock press.
The effects of low-level radiation on human health are not well understood, and so the models used, notably the linear no threshold model, are open to question. [105] Given these factors, studies of Chernobyl's health effects have come up with different conclusions and are sometimes the subject of scientific and political controversy.
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