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Zolpidem is a nonbenzodiazepine or Z-drug which acts as a sedative and hypnotic. [ 10][ 16] Zolpidem is a GABA A receptor agonist of the imidazopyridine class. [ 10] It works by increasing GABA effects in the central nervous system by binding to GABA A receptors at the same location as benzodiazepines. [ 10]
Chemical structure of the prototypical Z-drug zolpidem. Nonbenzodiazepines (/ ˌ n ɒ n ˌ b ɛ n z oʊ d aɪ ˈ æ z ɪ p iː n,-ˈ eɪ-/ [1] [2]), sometimes referred to colloquially as Z-drugs (as many of their names begin with the letter "z"), are a class of psychoactive, depressant, sedative, hypnotic, anxiolytic drugs that are benzodiazepine-like in uses, such as for treating insomnia [3 ...
Side Effects is a 2013 American psychological thriller film directed by Steven Soderbergh and written by Scott Z. Burns. It stars Rooney Mara as a woman who is prescribed experimental drugs by psychiatrists ( Jude Law and Catherine Zeta-Jones) after her husband ( Channing Tatum) is released from prison. Side Effects was released in the United ...
You probably know it as a sleeping pill, but it’s more accurately classified as a sedative-hypnotic, and doesn’t actually induce natural sleep.
Aponal, Quitaxon, Sinequan ( doxepin) – a tricyclic antidepressant used to treat nerve pain, insomnia; similar to imipramine. Anquil ( benperidol) – an antipsychotic primarily used to control antisocial hypersexual behaviour. Aricept ( donepezil) – used to slow the progression of Alzheimer's disease. Ativan ( lorazepam) – a ...
When it comes to prescription sleep aids, such as Ambien (zolpidem), Sonata (zaleplon), and Restoril (temazepam, a highly addictive benzodiazepine), all are explicitly not to be used in children.
Brotizolam [3] (marketed under brand name Lendormin) is a sedative-hypnotic [4] thienotriazolodiazepine [5] drug which is a benzodiazepine analog. [6] It possesses anxiolytic, anticonvulsant, hypnotic, sedative and skeletal muscle relaxant properties, and is considered to be similar in effect to other short-acting hypnotic benzodiazepines such as triazolam or midazolam. [7]
The company saw its new drug as a major innovation, emphasizing that the medication acted on an entirely different mechanism within the brain than the previous generation of insomnia medicines like Ambien and Lunesta. During the drug’s development, Merck had suggested that it could treat insomnia more effectively and produce fewer side ...
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