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Suvorexant, sold under the brand name Belsomra, is an orexin antagonist medication which is used in the treatment of insomnia. [2] [6] It is indicated specifically for the treatment of insomnia characterized by difficulties with sleep onset and/or maintenance in adults. [2] [6] Suvorexant helps with falling asleep faster, sleeping longer, being ...
Eszopiclone, sold under the brand name Lunesta among others, is a medication used in the treatment of insomnia. [3] [4] Evidence supports slight to moderate benefit up to six months. [5] [4] [6] It is taken by mouth. [3] [5] Common side effects include headache, dry mouth, nausea, and dizziness. [5]
Melatonin, an indoleamine, is a natural compound produced by various organisms, including bacteria and eukaryotes. [1] Its discovery in 1958 by Aaron B. Lerner and colleagues stemmed from the isolation of a substance from the pineal gland of cows that could induce skin lightening in common frogs.
With melatonin use increasing five-fold from 2000 to 2018, it’s become a popular sleep aid with an increasing number of options available at drugstores. You may be tempted to grab the first ...
In sleep medicine, we use very small doses of melatonin multiple hours before bed to help gradually shift the body’s clock (circadian rhythm) in people with delayed sleep phase disorder, jet lag ...
In medical literature from Australia, Irealnd, the UK, Canada, and the United States, temazepam is the only benzodiazepine which has been fatal in overdoses without combination with other CNS depresssants. This unique feature is due to the toxicity of the drug, which numerous studies have ranked it as being most toxic.
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