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The most common antibody isotype involved in warm antibody AIHA is IgG, though sometimes IgA is found. The IgG antibodies attach to a red blood cell, leaving their F C portion exposed with maximal reactivity at 37 °C (versus cold antibody induced hemolytic anemia whose antibodies only bind red blood cells at low body temperatures, typically 28–31 °C).
CREST syndrome, also known as the limited cutaneous form of systemic sclerosis (lcSSc), is a multisystem connective tissue disorder.The acronym "CREST" refers to the five main features: calcinosis, Raynaud's phenomenon, esophageal dysmotility, sclerodactyly, and telangiectasia.
ICD-9. 88.8. MeSH. D013817. [ edit on Wikidata] Non-contact thermography, thermographic imaging, or medical thermology is the field of thermography that uses infrared images of the human skin to assist in the diagnosis and treatment of medical conditions. Medical thermology is sometimes referred to as medical infrared imaging or tele-thermology ...
If you test negative with a PCR test, you are likely not contagious. But if you test negative with an at-home test, the answer will depend in part "on whether the negative COVID test is at the ...
Paroxysmal cold hemoglobinuria ( PCH) or Donath–Landsteiner hemolytic anemia ( DLHA) is an autoimmune hemolytic anemia featured by complement -mediated intravascular hemolysis after cold exposure. [ 1] It can present as an acute non-recurrent postinfectious event in children, or chronic relapsing episodes in adults with hematological ...
AIHA is a relatively rare condition, with an incidence of 5–10 cases per 1 million persons per year in the warm-antibody type and 0.45 to 1.9 cases per 1 million persons per year in the cold-antibody type. [4] Autoimmune hemolysis might be a precursor of later onset systemic lupus erythematosus. [5]
Post-exertional malaise ( PEM ), sometimes referred to as post-exertional symptom exacerbation ( PESE) [ 1] or post-exertional neuroimmune exhaustion (PENE), [ 2] is a worsening of symptoms that occurs after minimal exertion. It is the hallmark symptom of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and common in long COVID and ...
Pathophysiology. Cold agglutinins, or cold autoantibodies, occur naturally in nearly all individuals. These natural cold autoantibodies occur at low titers, less than 1:64 measured at 4 °C, and have no activity at higher temperatures. Pathologic cold agglutinins occur at titers over 1:1000 and react at 28-31 °C and sometimes at 37 °C.