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Duloxetine, sold under the brand name Cymbalta among others, [ 1] is a medication used to treat major depressive disorder, generalized anxiety disorder, obsessive-compulsive disorder, fibromyalgia, neuropathic pain and central sensitization. [ 7][ 8] It is taken by mouth. [ 7]
The use of medication in the treatment of fibromyalgia is debated [17] [18] although antidepressants can improve quality of life. [19] Common helpful medications include other serotonin–norepinephrine reuptake inhibitors, nonsteroidal anti-inflammatory drugs, and muscle relaxants. [20]
A 2004 review found benefit for fibromyalgia symptoms, with a reported number needed to treat of 4.8 (meaning that 1 person out of every 4.8 benefits from treatment) for pain reduction, but no change in fatigue or tender points. [15] A 2009 Cochrane review found insufficient evidence to justify its use in myofascial pain syndrome. [16]
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Serotonin–norepinephrine reuptake inhibitors ( SNRIs) are a class of antidepressant medications used to treat major depressive disorder (MDD), anxiety disorders, social phobia, chronic neuropathic pain, fibromyalgia syndrome (FMS), and menopausal symptoms. Off-label uses include treatments for attention-deficit hyperactivity disorder (ADHD ...
02:45. Semaglutide for weight loss has been in shortage since 2022, according to the FDA’s drug shortage database. Tirzepatide, which was approved for weight loss in the U.S. only in November ...
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