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The human thyroid (tan), as viewed from the front; and arteries (red) supplying the gland. The thyroid gland is a butterfly-shaped gland located in the neck below the Adam's apple. The thyroid, or thyroid gland, is an endocrine gland in vertebrates. In humans, it is in the neck and consists of two connected lobes.
Frequency. 0.3–0.4% (USA) [8] Hypothyroidism (also called underactive thyroid, low thyroid or hypothyreosis) is a disorder of the endocrine system in which the thyroid gland does not produce enough thyroid hormones. [3] It can cause a number of symptoms, such as poor ability to tolerate cold, extreme fatigue, muscle aches, constipation, slow ...
The major form of thyroid hormone in the blood is thyroxine (T 4), whose half-life of around one week is longer than that of T 3. In humans, the ratio of T 4 to T 3 released into the blood is approximately 14:1. T 4 is converted to the active T 3 (three to four times more potent than T 4) within cells by deiodinases (5′-deiodinase).
The less T3 and T4 your body produces, the less your body burns calories for fuel which can lead to weight gain, per a study in the International journal of general medicine. That said ...
Thyroid-stimulating hormone (also known as thyrotropin, thyrotropic hormone, or abbreviated TSH) is a pituitary hormone that stimulates the thyroid gland to produce thyroxine (T 4 ), and then triiodothyronine (T 3) which stimulates the metabolism of almost every tissue in the body. [1] It is a glycoprotein hormone produced by thyrotrope cells ...
In any case, the concentration of T 3 in the human blood plasma is about one-fortieth that of T 4. The half-life of T 3 is about 2.5 days. The half-life of T 4 is about 6.5 days. T 3 levels start to rise 45 minutes after administration and peak at about 2.5 hours.
Thyroid function tests ( TFTs) is a collective term for blood tests used to check the function of the thyroid. [1] TFTs may be requested if a patient is thought to suffer from hyperthyroidism (overactive thyroid) or hypothyroidism (underactive thyroid), or to monitor the effectiveness of either thyroid-suppression or hormone replacement therapy ...
Hashimoto's thyroiditis affects about 5% of Caucasians at some point in their lives. [4] It is the most common cause of hypothyroidism in iodine-sufficient areas of the world. [12] It typically begins between the ages of 30 and 50 and is much more common in women than men.
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