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Zolpidem is a nonbenzodiazepine or Z-drug which acts as a sedative and hypnotic. [ 10][ 16] Zolpidem is a GABA A receptor agonist of the imidazopyridine class. [ 10] It works by increasing GABA effects in the central nervous system by binding to GABA A receptors at the same location as benzodiazepines. [ 10]
Chemical structure of the prototypical Z-drug zolpidem. Nonbenzodiazepines (/ ˌ n ɒ n ˌ b ɛ n z oʊ d aɪ ˈ æ z ɪ p iː n,-ˈ eɪ-/ [1] [2]), sometimes referred to colloquially as Z-drugs (as many of their names begin with the letter "z"), are a class of psychoactive, depressant, sedative, hypnotic, anxiolytic drugs that are benzodiazepine-like in uses, such as for treating insomnia [3 ...
Sedation is the side effect people taking lorazepam most frequently report. In a group of around 3,500 people treated for anxiety, the most common side effects complained of from lorazepam were sedation (15.9%), dizziness (6.9%), weakness (4.2%), and unsteadiness (3.4%). Side effects such as sedation and unsteadiness increased with age. [52]
Currently, semaglutide (the medication in Ozempic) is approved only for type 2 diabetes and obesity treatment, although evidence shows that it can reduce the risk of heart disease, Stanford noted.
They are not recommended as the first-line anti-anxiety drugs, but they can be used in combination with SSRIs/SNRIs during the initial treatment stage. [4] Indications include panic disorder, sleep disorders, seizures, acute behavioral disturbance, muscle spasm and premedication and sedation for procedures.
According to the Anxiety and Depression Association of America (ADAA), 6.8 million adults have GAD. Other anxiety disorders include obsessive-compulsive disorder, panic disorder, post-traumatic ...
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