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Key:RMRCNWBMXRMIRW-WYVZQNDMSA-L Y. Vitamin B12, also known as cobalamin, is a water-soluble vitamin involved in metabolism. [ 2] It is one of eight B vitamins. It is required by animals, which use it as a cofactor in DNA synthesis, and in both fatty acid and amino acid metabolism. [ 3]
6% (< 60 years old), 20% (> 60 years old) [ 4] Vitamin B12 deficiency, also known as cobalamin deficiency, is the medical condition in which the blood and tissue have a lower than normal level of vitamin B 12. [ 5] Symptoms can vary from none to severe. [ 1] Mild deficiency may have few or absent symptoms. [ 1]
Cyanocobalamin is a form of vitamin B. 12 used to treat and prevent vitamin B. 12 deficiency except in the presence of cyanide toxicity. [ 7][ 8][ 2] The deficiency may occur in pernicious anemia, following surgical removal of the stomach, with fish tapeworm, or due to bowel cancer.
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In a newly diagnosed vitamin B 12-deficient patient, normally defined as when serum levels are less than 200 pg/ml, daily IM injections of hydroxocobalamin up to 1,000 μg (1 mg) per day are given to replenish the body's depleted cobalamin stores. In the presence of neurological symptoms, following daily treatment, injections up to weekly or ...
Adenosylcobalamin. Adenosylcobalamin (AdoCbl), also known as coenzyme B12, cobamamide, and dibencozide, is, along with methylcobalamin (MeCbl), one of the biologically active forms of vitamin B 12. [ 1] Adenosylcobalamin participates as a cofactor in radical-mediated 1,2-carbon skeleton rearrangements. These processes require the formation of ...
1 per 1000 people [ 8] Pernicious anemia is a disease where not enough red blood cells are produced due to a deficiency of vitamin B 12. [ 5] Those affected often have a gradual onset. [ 5] The most common initial symptoms are feeling tired and weak. [ 4]
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