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  2. Thyroid function tests - Wikipedia

    en.wikipedia.org/wiki/Thyroid_function_tests

    The total T4 is less useful in cases where there could be protein abnormalities. The total T4 is less accurate due to the large amount of T4 that is bound. The total T3 is measured in clinical practice since the T3 has decreased amount that is bound as compared to T4. [citation needed] Reference ranges depend on the method of analysis.

  3. Thyroid hormones - Wikipedia

    en.wikipedia.org/wiki/Thyroid_hormones

    Thyroid hormones are any hormones produced and released by the thyroid gland, namely triiodothyronine ( T3) and thyroxine ( T4 ). They are tyrosine -based hormones that are primarily responsible for regulation of metabolism. T 3 and T 4 are partially composed of iodine, derived from food. [ 2] A deficiency of iodine leads to decreased ...

  4. Thyroid - Wikipedia

    en.wikipedia.org/wiki/Thyroid

    The follicular lumen is filled with colloid, a concentrated solution of thyroglobulin and is the site of synthesis of the thyroid hormones thyroxine (T4) and triiodothyronine (T3). [16] Parafollicular cells. Scattered among follicular cells and in spaces between the spherical follicles are another type of thyroid cell, parafollicular cells. [4]

  5. Levothyroxine - Wikipedia

    en.wikipedia.org/wiki/Levothyroxine

    The T4T3 conversion is mediated by the selenoenzyme iodothyronine deiodinase. T3-thyroxine is a unique example of an iodine compound that is essential for human health. [38] [39] T 3 binds to thyroid receptor proteins in the cell nucleus and causes metabolic effects through the control of DNA transcription and protein synthesis. [24]

  6. Hyperthyroidism - Wikipedia

    en.wikipedia.org/wiki/Hyperthyroidism

    Hyperthyroidism is the condition that occurs due to excessive production of thyroid hormones by the thyroid gland. [3] Thyrotoxicosis is the condition that occurs due to excessive thyroid hormone of any cause and therefore includes hyperthyroidism. [3] Some, however, use the terms interchangeably. [5]

  7. Thyroid disease - Wikipedia

    en.wikipedia.org/wiki/Thyroid_disease

    When circulating in the body, T3 and T4 are bound to transport proteins. Only a small fraction of the circulating thyroid hormones are unbound or free, and thus biologically active. T3 and T4 levels can thus be measured as free T3 and T4, or total T3 and T4, which takes into consideration the free hormones in addition to the protein-bound hormones.

  8. Hypothyroidism - Wikipedia

    en.wikipedia.org/wiki/Hypothyroidism

    Frequency. 0.3–0.4% (USA) [8] Hypothyroidism (also called underactive thyroid, low thyroid or hypothyreosis) is a disorder of the endocrine system in which the thyroid gland does not produce enough thyroid hormones. [3] It can cause a number of symptoms, such as poor ability to tolerate cold, extreme fatigue, muscle aches, constipation, slow ...

  9. Thyroid disease in women - Wikipedia

    en.wikipedia.org/wiki/Thyroid_disease_in_women

    The thyroid makes hormones called T3 and T4 that regulate how the body uses energy. Thyroid hormone levels are controlled by the pituitary gland , which is a pea-sized gland in the brain. It makes thyroid stimulating hormone (TSH), which triggers the thyroid to make thyroid hormone.

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