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Atypical antipsychotics include: Amisulpride (Solian) – approved in low doses as a monotherapy for persistent depression. Lumateperone (Caplyta) – approved as a monotherapy for bipolar depression. Lurasidone (Latuda) – approved as a monotherapy for bipolar depression. Quetiapine (Seroquel) – approved as a monotherapy for bipolar depression.
Escitalopram. Escitalopram, sold under the name Lexapro, is most commonly used to treat depression and generalized anxiety disorder (GAD). According to a 2018 review, escitalopram is one of the ...
Adjunct medications are an umbrella category of substances that increase the potency or "enhance" antidepressants. [245] They work by affecting variables very close to the antidepressant, sometimes affecting a completely different mechanism of action. This may be attempted when depression treatments have not been successful in the past.
This is a list of investigational antidepressants, or drugs that are currently under development for clinical use in the treatment of depression but are not yet approved. . Specific indications include major depressive disorder, treatment-resistant depression, bipolar depression, and postpartum depression, among oth
Sertraline, sold under the brand name Zoloft among others, is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. [10] The effectiveness of sertraline for depression is similar to that of other antidepressants, and the differences are mostly confined to side effects. Sertraline is better tolerated than the older ...
Bupropion was originally called by the generic name amfebutamone, before being renamed in 2000. [ 16] In 2021, it was the eighteenth most commonly prescribed medication in the United States, with more than 29 million prescriptions. [ 38][ 39] It is on the World Health Organization's List of Essential Medicines.
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