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U.S. Route 50 (US 50) runs east–west across the southern part of the state of Ohio, passing through Cincinnati, Chillicothe, and Athens. It is mainly a two-lane road except for the easternmost and westernmost parts.
Traveling west to east, Route 50 begins with a stretch of very charming towns in Southwest Ohio. Near Cincinnati, a small stretch of the drive runs along The Ohio River Scenic Byway, which is a gorgeous route that features great views of the river, too!
U.S. Route 50 or U.S. Highway 50 (US 50) is a major east–west route of the U.S. Highway system, stretching 3,019 miles (4,859 km) from Interstate 80 (I-80) in West Sacramento, California, to Maryland Route 528 (MD 528) in Ocean City, Maryland, on the Atlantic Ocean.
Near Cincinnati, a small stretch of the route runs along The Ohio River Scenic Byway, which is a gorgeous route that features great views of the river. You'll likely notice several historic markers as you pass through small towns and villages, as Route 50 follows the footsteps of pioneers.
A road trip along US-50 follows time from colonial-era landscapes through the Wild West to high-tech Silicon Valley, the best route for the unhurried.
Travel US 50 through Ohio, OH. The Buckeye State. The Heart of It All! Columbus is the Capital. State motto is: With God, all things are possible.
Highway 50 winds from the cities of Washington, D.C., Cincinnati, St. Louis, Kansas City, and Sacramento, to the remote mountains of the West Virginia Appalachians and Colorado’s Rockies, to the vast farming country of the Midwest and Ohio River Valley, and ultimately through the now-legendary loneliness of Nevada and Utah’s Great Basin Desert.
US Route 50 in Ohio offers one of the most breathtaking and memorable road trips you can embark on. Spanning about 200 miles, this route is a treasure trove of scenic beauty, charming towns, and hidden gems waiting to be discovered. Are you ready to explore this enchanting stretch of road? 1. Cincinnati.
U.S. Route 50 (US 50) is a major east–west highway, connecting Ocean City, Maryland and West Sacramento, California. Stretching 3,000 miles (4,800 km), the route runs through mostly rural areas in the Western part of US. It includes the section through Nevada known as “The Loneliest Road in America”. All the way across the country, US-50 ...
Winding along the Ohio River from Indiana, US-50 cuts east from Cincinnati across the hill-and-valley country of southern Ohio before finally crossing the Ohio River into West Virginia.