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Alanine transaminase ( ALT ), also known as alanine aminotransferase ( ALT or ALAT ), formerly serum glutamate-pyruvate transaminase ( GPT) or serum glutamic-pyruvic transaminase ( SGPT ), is a transaminase enzyme ( EC 2.6.1.2) that was first characterized in the mid-1950s by Arthur Karmen and colleagues. [ 1]
AST/ALT ratio. LOINC. 16325-3, 1916-6. The AST/ALT ratio or De Ritis ratio is the ratio between the concentrations of two enzymes, aspartate transaminase (AST) and alanine transaminase, aka alanine aminotransferase (ALT), in the blood of a human or animal. It is used as one of several liver function tests, and measured with a blood test.
Liver function tests. Liver function tests ( LFTs or LFs ), also referred to as a hepatic panel, are groups of blood tests that provide information about the state of a patient's liver. [ 1] These tests include prothrombin time (PT/INR), activated partial thromboplastin time (aPTT), albumin, bilirubin (direct and indirect), and others.
Frequency. 70% (elderly inpatients) Hypoalbuminemia (or hypoalbuminaemia) is a medical sign in which the level of albumin in the blood is low. [ 1] This can be due to decreased production in the liver, increased loss in the gastrointestinal tract or kidneys, increased use in the body, or abnormal distribution between body compartments.
T cell deficiency is a deficiency of T cells, caused by decreased function of individual T cells, it causes an immunodeficiency of cell-mediated immunity. [ 1] T cells normal function is to help with the human body's immunity, they are one of the two primary types of lymphocytes (the other being B cells ). [medical citation needed]
Thyroid disease is a medical condition that affects the function of the thyroid gland. The thyroid gland is located at the front of the neck and produces thyroid hormones [ 1] that travel through the blood to help regulate many other organs, meaning that it is an endocrine organ. These hormones normally act in the body to regulate energy use ...
In medicine, the presence of elevated transaminases, commonly the transaminases alanine transaminase (ALT) and aspartate transaminase (AST), may be an indicator of liver dysfunction. [ 1][ 2] Other terms include transaminasemia, [ 3] and elevated liver enzymes (though they are not the only enzymes in the liver).
Reverse T 3 is the third-most common iodothyronine the thyroid gland releases into the bloodstream, at 0.9%; tetraiodothyronine (levothyroxine, T 4) constitutes 90% and T 3 is 9%. However, 95% of rT 3 in human blood is made elsewhere in the body, as enzymes remove a particular iodine atom from T 4. [ 1]
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