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Red blood cell distribution width ( RDW ), as well as various types thereof ( RDW-CV or RCDW and RDW-SD ), is a measure of the range of variation of red blood cell (RBC) volume that is reported as part of a standard complete blood count. [ 1] Red blood cells have an average volume of 80–100 femtoliters, but individual cell volumes vary even ...
Hereditary spherocytosis ( HS) is a congenital hemolytic disorder wherein a genetic mutation coding for a structural membrane protein phenotype causes the red blood cells to be sphere-shaped ( spherocytosis ), rather than the normal biconcave disk shape. This abnormal shape interferes with the cells' ability to flex during blood circulation ...
Anemia or anaemia ( British English) is a blood disorder in which the blood has a reduced ability to carry oxygen. This can be due to a lower than normal number of red blood cells, a reduction in the amount of hemoglobin available for oxygen transport, or abnormalities in hemoglobin that impair its function. [ 3][ 4]
Sideroblastic anemia. Sideroblastic anemia, or sideroachrestic anemia, is a form of anemia in which the bone marrow produces ringed sideroblasts rather than healthy red blood cells (erythrocytes). [ 1] In sideroblastic anemia, the body has iron available but cannot incorporate it into hemoglobin, which red blood cells need in order to transport ...
Red blood cell distribution width (RDW or RDW-CV or RCDW and RDW-SD) is a measure of the range of variation of red blood cell (RBC) volume, yielding clues about morphology. [ citation needed ] Erythropoietic precursor indices
Spherocytosis is the presence of spherocytes in the blood, i.e. erythrocytes ( red blood cells) that are sphere-shaped rather than bi-concave disk shaped as normal. Spherocytes are found in all hemolytic anemias to some degree. Hereditary spherocytosis and autoimmune hemolytic anemia are characterized by having only spherocytes.
A complete blood count ( CBC ), also known as a full blood count ( FBC ), is a set of medical laboratory tests that provide information about the cells in a person's blood. The CBC indicates the counts of white blood cells, red blood cells and platelets, the concentration of hemoglobin, and the hematocrit (the volume percentage of red blood ...
An anemia is a red blood cell defect that can lead to an undersupply of oxygen. [ 1] Megaloblastic anemia results from inhibition of DNA synthesis during red blood cell production. [ 2] When DNA synthesis is impaired, the cell cycle cannot progress from the G2 growth stage to the mitosis (M) stage. This leads to continuing cell growth without ...
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