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Aplastic anemia [2] (AA) [3] is a severe hematologic condition in which the body fails to make blood cells in sufficient numbers. Blood cells are produced in the bone marrow by stem cells that reside there. [4] Aplastic anemia causes a deficiency of all blood cell types: red blood cells, white blood cells, and platelets. [5] [6]
Pure red cell aplasia affects the red blood cells in particular. Pure red cell aplasia ( PRCA) or erythroblastopenia refers to a type of aplastic anemia affecting the precursors to red blood cells but usually not to white blood cells. In PRCA, the bone marrow ceases to produce red blood cells. There are multiple etiologies that can cause PRCA.
Aplastic anemia [31] affects all kinds of blood cells. Fanconi anemia is a hereditary disorder or defect featuring aplastic anemia and various other abnormalities. Anemia of kidney failure [31] due to insufficient production of the hormone erythropoietin; Anemia of endocrine disease [32] Disturbance of proliferation and maturation of erythroblasts
An anemia is a red blood cell defect that can lead to an undersupply of oxygen. [ 1] Megaloblastic anemia results from inhibition of DNA synthesis during red blood cell production. [ 2] When DNA synthesis is impaired, the cell cycle cannot progress from the G2 growth stage to the mitosis (M) stage. This leads to continuing cell growth without ...
t. e. Aplasia ( / əˈpleɪʒə / ⓘ; from Greek a, "not", "no" + plasis, "formation") is a birth defect where an organ or tissue is wholly or largely absent. It is caused by a defect in a developmental process. [ 1][ 2] Aplastic anemia is the failure of the body to produce blood cells.
Agranulocytosis. Agranulocytosis, also known as agranulosis or granulopenia, is an acute condition involving a severe and dangerous lowered white blood cell count ( leukopenia, most commonly of neutrophils) and thus causing neutropenia in the circulating blood. [ 1] It is a severe lack of one major class of infection-fighting white blood cells.
a B2 deficiency [3] a B6 deficiency [3] or a mixture of conditions producing microcytic and macrocytic anemia. [1] Blood loss, suppressed production of RBCs or hemolysis represent most cases of normocytic anemia. In blood loss, morphologic findings are generally unremarkable, except after 12 to 24 hrs where polychromasia appears.
An anemia is a decrease in number of red blood cells (RBCs) or less than the normal quantity of hemoglobin in the blood. [2] [3] However, it can include decreased oxygen-binding ability of each hemoglobin molecule due to deformity or lack in numerical development as in some other types of hemoglobin deficiency.
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