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Atorvastatin is a statin medication used to prevent cardiovascular disease in those at high risk and to treat abnormal lipid levels. [ 4] For the prevention of cardiovascular disease, statins are a first-line treatment. [ 4] It is taken by mouth.
Lovastatin, a compound isolated from Aspergillus terreus, was the first statin to be marketed. Statins (or HMG-CoA reductase inhibitors) are a class of medications that reduce illness and mortality in people who are at high risk of cardiovascular disease. They are the most commonly prescribed cholesterol-lowering drugs.
Lipid-lowering agents, also sometimes referred to as hypolipidemic agents, cholesterol-lowering drugs, or antihyperlipidemic agents are a diverse group of pharmaceuticals that are used to lower the level of lipids and lipoproteins, such as cholesterol, in the blood ( hyperlipidemia ). The American Heart Association recommends the descriptor ...
Jb Reed, Bloomberg via Getty Images By Emily Jane Fox CVS (CVS) charges $150 for a monthly prescription of the generic version of the cholesterol drug Lipitor. The same drug goes for $17 at Costco.
The discovery of HMG-CoA (3-hydroxy-3-methylglutaryl-CoA) reductase inhibitors, called statins, was a breakthrough in the prevention of hypercholesterolemia and related diseases. Hypercholesterolemia is considered to be one of the major risk factors for atherosclerosis which often leads to cardiovascular, cerebrovascular and peripheral vascular ...
Aponal, Quitaxon, Sinequan ( doxepin) – a tricyclic antidepressant used to treat nerve pain, insomnia; similar to imipramine. Anquil ( benperidol) – an antipsychotic primarily used to control antisocial hypersexual behaviour. Aricept ( donepezil) – used to slow the progression of Alzheimer's disease. Ativan ( lorazepam) – a ...
Lovastatin is an inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMG-CoA reductase), an enzyme that catalyzes the conversion of HMG-CoA to mevalonate. [ 15] Mevalonate is a required building block for cholesterol biosynthesis and lovastatin interferes with its production by acting as a reversible competitive inhibitor for HMG-CoA ...
Rosuvastatin. Rosuvastatin, sold under the brand name Crestor among others, is a statin medication, used to prevent cardiovascular disease in those at high risk and treat abnormal lipids. [ 6] It is recommended to be used together with dietary changes, exercise, and weight loss. [ 6] It is taken orally (by mouth).
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