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Immunoglobulin M. Immunoglobulin M ( IgM) is the largest of several isotypes of antibodies (also known as immunoglobulin) that are produced by vertebrates. IgM is the first antibody to appear in the response to initial exposure to an antigen; [1] [2] causing it to also be called an acute phase antibody. In humans and other mammals that have ...
Specialty. Nephrology. IgM nephropathy or immunoglobulin M nephropathy (IgMN) is a kind of idiopathic glomerulonephritis that is marked by IgM diffuse deposits in the glomerular mesangium. [1] IgM nephropathy was initially documented in 1978 by two separate teams of researchers. [2]
Intersex medical interventions ( IMI ), sometimes known as intersex genital mutilations ( IGM ), [1] are surgical, hormonal and other medical interventions performed to modify atypical or ambiguous genitalia and other sex characteristics, primarily for the purposes of making a person's appearance more typical and to reduce the likelihood of ...
Hematology. Isolated primary immunoglobulin M deficiency [1] is a poorly defined dysgammaglobulinemia characterized by decreased levels of IgM while levels of other immunoglobulins are normal. The immunodeficiency has been associated with some clinical disorders including recurrent infections, atopy, Bloom's syndrome, celiac disease, systemic ...
Hypergammaglobulinemia is a condition that is characterized by the increased levels of a certain immunoglobulin in the blood serum. [1] The name of the disorder refers to an excess of proteins after serum protein electrophoresis (found in the gammaglobulin region). [citation needed] Most hypergammaglobulinemias are caused by an excess of ...
Hyper IgM syndrome is a rare primary immune deficiency disorders characterized by low or absent levels of serum IgG, IgA, IgE and normal or increased levels of serum IgM. [8] They are resulting from mutations in the pathway from B-cell activation to isotype class switching. Patients with HIGM are usually diagnosed within the first two years of ...
Here are 10 things you need to know about Broadcom's imminent stock split. 1. Broadcom is (sort of) making history. On June 12, when Broadcom released its fiscal second-quarter operating results ...
IG Metall ( German: [iːɡeː meˈtal] ⓘ; IGM; German: Industriegewerkschaft Metall, "Industrial Union of Metalworkers'") is the dominant metalworkers ' union in Germany, making it the country's largest union [1] as well as Europe's largest industrial union. [2] Analysts of German labor relations consider it a major trend-setter in national ...